3d3l: Difference between revisions
Jump to navigation
Jump to search
New page: '''Unreleased structure''' The entry 3d3l is ON HOLD Authors: Tresaugues, L., Moche, M., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin,... |
No edit summary |
||
(10 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
The | ==The 2.6 A crystal structure of the lipoxygenase domain of human arachidonate 12-lipoxygenase, 12S-type== | ||
<StructureSection load='3d3l' size='340' side='right'caption='[[3d3l]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3d3l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D3L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3l OCA], [https://pdbe.org/3d3l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d3l RCSB], [https://www.ebi.ac.uk/pdbsum/3d3l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d3l ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LOX12_HUMAN LOX12_HUMAN] Oxygenase and 14,15-leukotriene A4 synthase activity. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/3d3l_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d3l ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Berglund H]] | |||
[[Category: Busam RD]] | |||
[[Category: Collins R]] | |||
[[Category: Dahlgren LG]] | |||
[[Category: Edwards AM]] | |||
[[Category: Flodin S]] | |||
[[Category: Flores A]] | |||
[[Category: Graslund S]] | |||
[[Category: Hammarstrom M]] | |||
[[Category: Herman MD]] | |||
[[Category: Johansson A]] | |||
[[Category: Johansson I]] | |||
[[Category: Kallas A]] | |||
[[Category: Karlberg T]] | |||
[[Category: Kotenyova T]] | |||
[[Category: Lehtio L]] | |||
[[Category: Moche M]] | |||
[[Category: Nilsson ME]] | |||
[[Category: Nordlund P]] | |||
[[Category: Nyman T]] | |||
[[Category: Olesen K]] | |||
[[Category: Persson C]] | |||
[[Category: Sagemark J]] | |||
[[Category: Schueler H]] | |||
[[Category: Svensson L]] | |||
[[Category: Thorsell AG]] | |||
[[Category: Tresaugues L]] | |||
[[Category: Van Den Berg S]] | |||
[[Category: Weigelt J]] | |||
[[Category: Welin M]] | |||
[[Category: Wikstrom M]] |
Latest revision as of 15:40, 30 August 2023
The 2.6 A crystal structure of the lipoxygenase domain of human arachidonate 12-lipoxygenase, 12S-typeThe 2.6 A crystal structure of the lipoxygenase domain of human arachidonate 12-lipoxygenase, 12S-type
Structural highlights
FunctionLOX12_HUMAN Oxygenase and 14,15-leukotriene A4 synthase activity. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
|
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Homo sapiens
- Large Structures
- Arrowsmith CH
- Berglund H
- Busam RD
- Collins R
- Dahlgren LG
- Edwards AM
- Flodin S
- Flores A
- Graslund S
- Hammarstrom M
- Herman MD
- Johansson A
- Johansson I
- Kallas A
- Karlberg T
- Kotenyova T
- Lehtio L
- Moche M
- Nilsson ME
- Nordlund P
- Nyman T
- Olesen K
- Persson C
- Sagemark J
- Schueler H
- Svensson L
- Thorsell AG
- Tresaugues L
- Van Den Berg S
- Weigelt J
- Welin M
- Wikstrom M