3d2o: Difference between revisions

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<StructureSection load='3d2o' size='340' side='right'caption='[[3d2o]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
<StructureSection load='3d2o' size='340' side='right'caption='[[3d2o]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3d2o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"diplococcus_gonorrhoeae"_(zopf_1885)_lehmann_and_neumann_1896 "diplococcus gonorrhoeae" (zopf 1885) lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D2O FirstGlance]. <br>
<table><tr><td colspan='2'>[[3d2o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D2O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3d1t|3d1t]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ngo0387 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=485 "Diplococcus gonorrhoeae" (Zopf 1885) Lehmann and Neumann 1896])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/GTP_cyclohydrolase_I GTP cyclohydrolase I], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.16 3.5.4.16] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d2o OCA], [https://pdbe.org/3d2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d2o RCSB], [https://www.ebi.ac.uk/pdbsum/3d2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d2o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d2o OCA], [https://pdbe.org/3d2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d2o RCSB], [https://www.ebi.ac.uk/pdbsum/3d2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d2o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/GCH4_NEIG1 GCH4_NEIG1]] Converts GTP to 7,8-dihydroneopterin triphosphate.<ref>PMID:17032654</ref>
[https://www.uniprot.org/uniprot/GCH4_NEIG1 GCH4_NEIG1] Converts GTP to 7,8-dihydroneopterin triphosphate.<ref>PMID:17032654</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: GTP cyclohydrolase I]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Swairjo, M A]]
[[Category: Neisseria gonorrhoeae]]
[[Category: Bimodular tunnel fold]]
[[Category: Swairjo MA]]
[[Category: Biosynthetic protein]]
[[Category: Folate biosynthesis]]
[[Category: Gtp cyclohydrolase]]
[[Category: Hydrolase]]
[[Category: Manganese]]
[[Category: Metalloenzyme]]
[[Category: Tunneling fold]]

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