3cgu: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3cgu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CGU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CGU FirstGlance]. <br> | <table><tr><td colspan='2'>[[3cgu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CGU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CGU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.51Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cgu OCA], [https://pdbe.org/3cgu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cgu RCSB], [https://www.ebi.ac.uk/pdbsum/3cgu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cgu ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cgu OCA], [https://pdbe.org/3cgu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cgu RCSB], [https://www.ebi.ac.uk/pdbsum/3cgu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cgu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/GIL_DROME GIL_DROME] Regulates cell determination; development of ommatidia and optic lobe. Is a signaling molecule involved in the process of axon pathfinding in the eye. Part of the Ras pathway regulating programmed cell death in pupal eyes; activated by lozenge (lz). Antagonist for the Egfr receptor (gurken). Inhibits Egfr signaling without interacting directly with the receptor, but instead by sequestering the Egfr-activating ligand spitz (spi).<ref>PMID:1628618</ref> <ref>PMID:1606617</ref> <ref>PMID:1286772</ref> <ref>PMID:10200472</ref> <ref>PMID:15329724</ref> <ref>PMID:15879554</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Klein | [[Category: Klein DE]] | ||
[[Category: Lemmon | [[Category: Lemmon MA]] | ||
[[Category: Stayrook | [[Category: Stayrook SE]] | ||