3c5c: Difference between revisions

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==Crystal structure of human Ras-like, family 12 protein in complex with GDP==
==Crystal structure of human Ras-like, family 12 protein in complex with GDP==
<StructureSection load='3c5c' size='340' side='right' caption='[[3c5c]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='3c5c' size='340' side='right'caption='[[3c5c]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3c5c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C5C FirstGlance]. <br>
<table><tr><td colspan='2'>[[3c5c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C5C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RASL12, RIS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c5c OCA], [http://pdbe.org/3c5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3c5c RCSB], [http://www.ebi.ac.uk/pdbsum/3c5c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3c5c ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c5c OCA], [https://pdbe.org/3c5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c5c RCSB], [https://www.ebi.ac.uk/pdbsum/3c5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c5c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RASLC_HUMAN RASLC_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/3c5c_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/3c5c_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Bochkarev, A]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C]]
[[Category: Bochkarev A]]
[[Category: Edwards, A M]]
[[Category: Bountra C]]
[[Category: Loppnau, P]]
[[Category: Edwards AM]]
[[Category: Park, H]]
[[Category: Loppnau P]]
[[Category: Structural genomic]]
[[Category: Park H]]
[[Category: Shen, L]]
[[Category: Shen L]]
[[Category: Tempel, W]]
[[Category: Tempel W]]
[[Category: Tong, Y]]
[[Category: Tong Y]]
[[Category: Weigelt, J]]
[[Category: Weigelt J]]
[[Category: Gdp]]
[[Category: Gtp-binding]]
[[Category: Gtpase]]
[[Category: Limited proteolysis]]
[[Category: Nucleotide-binding]]
[[Category: Ra]]
[[Category: Rasl12]]
[[Category: Sgc]]
[[Category: Signaling protein]]

Latest revision as of 15:22, 30 August 2023

Crystal structure of human Ras-like, family 12 protein in complex with GDPCrystal structure of human Ras-like, family 12 protein in complex with GDP

Structural highlights

3c5c is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RASLC_HUMAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3c5c, resolution 1.85Å

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OCA
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