3c5c: Difference between revisions

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[[Image:3c5c.jpg|left|200px]]<br /><applet load="3c5c" size="350" color="white" frame="true" align="right" spinBox="true"
caption="3c5c, resolution 1.850&Aring;" />
'''Crystal structure of human Ras-like, family 12 protein in complex with GDP'''<br />


==About this Structure==
==Crystal structure of human Ras-like, family 12 protein in complex with GDP==
3C5C is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=GDP:'>GDP</scene> and <scene name='pdbligand=UNX:'>UNX</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Mg+Binding+Site+For+Residue+A+202'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+B+202'>AC2</scene>, <scene name='pdbsite=AC3:Mg+Binding+Site+For+Residue+C+202'>AC3</scene>, <scene name='pdbsite=AC4:Mg+Binding+Site+For+Residue+D+202'>AC4</scene>, <scene name='pdbsite=AC5:Mg+Binding+Site+For+Residue+A+203'>AC5</scene>, <scene name='pdbsite=AC6:Mg+Binding+Site+For+Residue+C+203'>AC6</scene>, <scene name='pdbsite=AC7:Mg+Binding+Site+For+Residue+B+203'>AC7</scene>, <scene name='pdbsite=AC8:Gdp+Binding+Site+For+Residue+A+201'>AC8</scene>, <scene name='pdbsite=AC9:Gdp+Binding+Site+For+Residue+B+201'>AC9</scene>, <scene name='pdbsite=BC1:Gdp+Binding+Site+For+Residue+C+201'>BC1</scene>, <scene name='pdbsite=BC2:Gdp+Binding+Site+For+Residue+D+201'>BC2</scene>, <scene name='pdbsite=BC3:Unx+Binding+Site+For+Residue+A+204'>BC3</scene>, <scene name='pdbsite=BC4:Unx+Binding+Site+For+Residue+D+203'>BC4</scene> and <scene name='pdbsite=BC5:Unx+Binding+Site+For+Residue+C+204'>BC5</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C5C OCA].  
<StructureSection load='3c5c' size='340' side='right'caption='[[3c5c]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3c5c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C5C FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c5c OCA], [https://pdbe.org/3c5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c5c RCSB], [https://www.ebi.ac.uk/pdbsum/3c5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c5c ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RASLC_HUMAN RASLC_HUMAN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/3c5c_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c5c ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev A]]
[[Category: Bountra, C.]]
[[Category: Bountra C]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Loppnau, P.]]
[[Category: Loppnau P]]
[[Category: Park, H.]]
[[Category: Park H]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Shen L]]
[[Category: Shen, L.]]
[[Category: Tempel W]]
[[Category: Tempel, W.]]
[[Category: Tong Y]]
[[Category: Tong, Y.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: GDP]]
[[Category: MG]]
[[Category: UNX]]
[[Category: gdp]]
[[Category: gtp-binding]]
[[Category: gtpase]]
[[Category: limited proteolysis]]
[[Category: nucleotide-binding]]
[[Category: ras]]
[[Category: rasl12]]
[[Category: sgc]]
[[Category: signaling protein]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:08:40 2008''

Latest revision as of 15:22, 30 August 2023

Crystal structure of human Ras-like, family 12 protein in complex with GDPCrystal structure of human Ras-like, family 12 protein in complex with GDP

Structural highlights

3c5c is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RASLC_HUMAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3c5c, resolution 1.85Å

Drag the structure with the mouse to rotate

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