3br1: Difference between revisions

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 ==Crystal Structure of the Complex of Dequalinium Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor==
-<StructureSection load='3br1' size='340' side='right' caption='[[3br1]], [[Resolution|resolution]] 3.31&Aring;' scene=''>
+<StructureSection load='3br1' size='340' side='right'caption='[[3br1]], [[Resolution|resolution]] 3.31&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3br1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BR1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BR1 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3br1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BR1 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DEQ:DEQUALINIUM'>DEQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.31&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jup|1jup]], [[1jus|1jus]], [[1jty|1jty]], [[1jt6|1jt6]], [[3bqz|3bqz]], [[3br0|3br0]], [[3br2|3br2]], [[3br3|3br3]], [[3br4|3br4]], [[3br5|3br5]], [[3br6|3br6]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DEQ:DEQUALINIUM'>DEQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">qacR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3br1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3br1 OCA], [https://pdbe.org/3br1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3br1 RCSB], [https://www.ebi.ac.uk/pdbsum/3br1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3br1 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3br1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3br1 OCA], [http://pdbe.org/3br1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3br1 RCSB], [http://www.ebi.ac.uk/pdbsum/3br1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3br1 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/QACR_STAAM QACR_STAAM]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).
+[https://www.uniprot.org/uniprot/QACR_STAAM QACR_STAAM] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3br1 ConSurf].
 <div style="clear:both"></div>
+==See Also==
+*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
+*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
 __TOC__
 </StructureSection>
-[[Category: Brooks, B E]]
+[[Category: Large Structures]]
-[[Category: Dequalinium]]
+[[Category: Staphylococcus aureus]]
-[[Category: Dna-binding]]
+[[Category: Brooks BE]]
-[[Category: Multidrug resistance]]
-[[Category: Plasmid]]
-[[Category: Qacr]]
-[[Category: Repressor]]
-[[Category: Tetr]]
-[[Category: Transcription]]
-[[Category: Transcription regulation]]