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< | ==Human Acyl-coenzyme A thioesterase 12== | ||
<StructureSection load='3b7k' size='340' side='right'caption='[[3b7k]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
You may | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3b7k]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B7K FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7k OCA], [https://pdbe.org/3b7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b7k RCSB], [https://www.ebi.ac.uk/pdbsum/3b7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b7k ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACO12_HUMAN ACO12_HUMAN] Hydrolyzes acetyl-CoA to acetate and CoA.<ref>PMID:16951743</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/3b7k_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b7k ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Thioesterase 3D structures|Thioesterase 3D structures]] | |||
== References == | |||
== | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: Berglund | [[Category: Berglund H]] | ||
[[Category: Busam | [[Category: Busam RD]] | ||
[[Category: Collins | [[Category: Collins R]] | ||
[[Category: Dahlgren | [[Category: Dahlgren LG]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Flodin | [[Category: Flodin S]] | ||
[[Category: Flores | [[Category: Flores A]] | ||
[[Category: Graslund | [[Category: Graslund S]] | ||
[[Category: Hallberg | [[Category: Hallberg BM]] | ||
[[Category: Hammarstrom | [[Category: Hammarstrom M]] | ||
[[Category: Herman | [[Category: Herman MD]] | ||
[[Category: Johansson | [[Category: Johansson A]] | ||
[[Category: Johansson | [[Category: Johansson I]] | ||
[[Category: Kallas | [[Category: Kallas A]] | ||
[[Category: Karlberg | [[Category: Karlberg T]] | ||
[[Category: Kotenyova | [[Category: Kotenyova T]] | ||
[[Category: Lehtio L]] | |||
[[Category: Lehtio | [[Category: Moche M]] | ||
[[Category: Moche | [[Category: Nilsson ME]] | ||
[[Category: Nilsson | [[Category: Nordlund P]] | ||
[[Category: Nordlund | [[Category: Nyman T]] | ||
[[Category: Nyman | [[Category: Persson C]] | ||
[[Category: Persson | [[Category: Sagemark J]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sagemark | [[Category: Svensson L]] | ||
[[Category: Sundstrom | [[Category: Thorsell AG]] | ||
[[Category: | [[Category: Tresaugues L]] | ||
[[Category: Van Den Berg S]] | |||
[[Category: | [[Category: Weigelt J]] | ||
[[Category: | [[Category: Welin M]] | ||
[[Category: | |||
[[Category: | |||
[[Category: | |||
Latest revision as of 15:03, 30 August 2023
Human Acyl-coenzyme A thioesterase 12Human Acyl-coenzyme A thioesterase 12
Structural highlights
FunctionACO12_HUMAN Hydrolyzes acetyl-CoA to acetate and CoA.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences |
|
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Homo sapiens
- Large Structures
- Arrowsmith CH
- Berglund H
- Busam RD
- Collins R
- Dahlgren LG
- Edwards AM
- Flodin S
- Flores A
- Graslund S
- Hallberg BM
- Hammarstrom M
- Herman MD
- Johansson A
- Johansson I
- Kallas A
- Karlberg T
- Kotenyova T
- Lehtio L
- Moche M
- Nilsson ME
- Nordlund P
- Nyman T
- Persson C
- Sagemark J
- Sundstrom M
- Svensson L
- Thorsell AG
- Tresaugues L
- Van Den Berg S
- Weigelt J
- Welin M