3b4t: Difference between revisions
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<StructureSection load='3b4t' size='340' side='right'caption='[[3b4t]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='3b4t' size='340' side='right'caption='[[3b4t]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3b4t]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3b4t]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B4T FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b4t OCA], [https://pdbe.org/3b4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b4t RCSB], [https://www.ebi.ac.uk/pdbsum/3b4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b4t ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b4t OCA], [https://pdbe.org/3b4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b4t RCSB], [https://www.ebi.ac.uk/pdbsum/3b4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b4t ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/RNPH_MYCTU RNPH_MYCTU] Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Antczak AJ]] | |||
[[Category: Antczak | [[Category: Berger JM]] | ||
[[Category: Berger | [[Category: Lekin T]] | ||
[[Category: Lekin | [[Category: Segelke BW]] | ||
[[Category: Segelke | |||
Latest revision as of 15:01, 30 August 2023
Crystal structure of Mycobacterium tuberculosis RNase PH, the Mycobacterium tuberculosis Structural Genomics Consortium target Rv1340Crystal structure of Mycobacterium tuberculosis RNase PH, the Mycobacterium tuberculosis Structural Genomics Consortium target Rv1340
Structural highlights
FunctionRNPH_MYCTU Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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