2zj0: Difference between revisions

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 ==Crystal structure of Mycobacterium tuberculosis S-Adenosyl-L-homocysteine hydrolase in ternary complex with NAD and 2-fluoroadenosine==
-<StructureSection load='2zj0' size='340' side='right' caption='[[2zj0]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
+<StructureSection load='2zj0' size='340' side='right'caption='[[2zj0]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2zj0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZJ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZJ0 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2zj0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZJ0 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2FA:2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL'>2FA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1li4|1li4]], [[2ziz|2ziz]], [[2zj1|2zj1]], [[3ce6|3ce6]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2FA:2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL'>2FA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ahcY, sahH, Rv3248c, MT3346, MTCY20B11.23c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zj0 OCA], [https://pdbe.org/2zj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zj0 RCSB], [https://www.ebi.ac.uk/pdbsum/2zj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zj0 ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteinase Adenosylhomocysteinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.1.1 3.3.1.1] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zj0 OCA], [http://pdbe.org/2zj0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zj0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zj0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zj0 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/SAHH_MYCTU SAHH_MYCTU]] May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity).[HAMAP-Rule:MF_00563]
+[https://www.uniprot.org/uniprot/SAHH_MYCTU SAHH_MYCTU] May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity).[HAMAP-Rule:MF_00563]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 38: / Line 36: @@
 __TOC__
 </StructureSection>
-[[Category: Adenosylhomocysteinase]]
+[[Category: Large Structures]]
-[[Category: Myctu]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
-[[Category: Gokulan, K]]
+[[Category: Gokulan K]]
-[[Category: Ioerger, T R]]
+[[Category: Ioerger TR]]
-[[Category: Owen, J L]]
+[[Category: Owen JL]]
-[[Category: Reddy, M C.M]]
+[[Category: Reddy MCM]]
-[[Category: Sacchettini, J C]]
+[[Category: Sacchettini JC]]
-[[Category: Shetty, N D]]
+[[Category: Shetty ND]]
-[[Category: 37 amino acid insertional region]]
-[[Category: Dimer of dimer]]
-[[Category: Hydrolase]]
-[[Category: Nad binding domain]]
-[[Category: One-carbon metabolism]]
-[[Category: Protein-substrate complex]]