2ypn: Difference between revisions
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==Hydroxymethylbilane synthase== | ==Hydroxymethylbilane synthase== | ||
<StructureSection load='2ypn' size='340' side='right' caption='[[2ypn]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2ypn' size='340' side='right'caption='[[2ypn]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ypn]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2ypn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YPN FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPM:3-[5-{[3-(2-CARBOXYETHYL)-4-(CARBOXYMETHYL)-5-METHYL-1H-PYRROL-2-YL]METHYL}-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC+ACID'>DPM</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPM:3-[5-{[3-(2-CARBOXYETHYL)-4-(CARBOXYMETHYL)-5-METHYL-1H-PYRROL-2-YL]METHYL}-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC+ACID'>DPM</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ypn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ypn OCA], [https://pdbe.org/2ypn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ypn RCSB], [https://www.ebi.ac.uk/pdbsum/2ypn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ypn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HEM3_ECOLI HEM3_ECOLI] Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.[HAMAP-Rule:MF_00260] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 25: | Line 25: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Campbell | [[Category: Campbell JW]] | ||
[[Category: Habash | [[Category: Habash J]] | ||
[[Category: Haedener | [[Category: Haedener A]] | ||
[[Category: Hao | [[Category: Hao Q]] | ||
[[Category: Helliwell | [[Category: Helliwell JR]] | ||
[[Category: Nieh | [[Category: Nieh YP]] | ||
[[Category: Raftery | [[Category: Raftery J]] | ||
[[Category: Schotte | [[Category: Schotte F]] | ||
[[Category: Ursby | [[Category: Ursby T]] | ||
[[Category: Weisgerber | [[Category: Weisgerber S]] | ||
[[Category: Wulff | [[Category: Wulff M]] | ||
Latest revision as of 14:59, 30 August 2023
Hydroxymethylbilane synthaseHydroxymethylbilane synthase
Structural highlights
FunctionHEM3_ECOLI Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.[HAMAP-Rule:MF_00260] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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