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==Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound== | ==Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound== | ||
<StructureSection load='2qkr' size='340' side='right' caption='[[2qkr]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2qkr' size='340' side='right'caption='[[2qkr]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2qkr]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2qkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QKR FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IXM:(Z)-1H,1H-[2,3]BIINDOLYLIDENE-3,2-DIONE-3-OXIME'>IXM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qkr OCA], [https://pdbe.org/2qkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qkr RCSB], [https://www.ebi.ac.uk/pdbsum/2qkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qkr ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q5CRJ8_CRYPI Q5CRJ8_CRYPI] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkr_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkr_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qkr ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Cryptosporidium parvum Iowa II]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Artz | [[Category: Artz JD]] | ||
[[Category: Bochkarev | [[Category: Bochkarev A]] | ||
[[Category: Dong | [[Category: Dong A]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Hassanali | [[Category: Hassanali A]] | ||
[[Category: Hui | [[Category: Hui R]] | ||
[[Category: Lew | [[Category: Lew J]] | ||
[[Category: Lin | [[Category: Lin YH]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sundstrom | [[Category: Weigelt J]] | ||
[[Category: Weigelt | [[Category: Wernimont AK]] | ||
[[Category: Wernimont | |||
Latest revision as of 14:35, 30 August 2023
Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime boundCryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound
Structural highlights
FunctionEvolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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