2qkr: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2qkr.jpg|left|200px]]
- {{Structure
+==Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound==
-|PDB= 2qkr |SIZE=350|CAPTION= <scene name='initialview01'>2qkr</scene>, resolution 2.600&Aring;
+<StructureSection load='2qkr' size='340' side='right'caption='[[2qkr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=IXM:(Z)-1H,1&#39;H-[2,3&#39;]BIINDOLYLIDENE-3,2&#39;-DIONE-3-OXIME'>IXM</scene>
+<table><tr><td colspan='2'>[[2qkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QKR FirstGlance]. <br>
-|ACTIVITY= [http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-|GENE= cgd5_2510 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 Cryptosporidium parvum Iowa II])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IXM:(Z)-1H,1H-[2,3]BIINDOLYLIDENE-3,2-DIONE-3-OXIME'>IXM</scene></td></tr>
-}}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qkr OCA], [https://pdbe.org/2qkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qkr RCSB], [https://www.ebi.ac.uk/pdbsum/2qkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qkr ProSAT]</span></td></tr>
+</table>
-'''Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound'''
+== Function ==
+[https://www.uniprot.org/uniprot/Q5CRJ8_CRYPI Q5CRJ8_CRYPI]
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-QKR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKR OCA].
+Check<jmol>
-[[Category: Cryptosporidium parvum iowa ii]]
+  <jmolCheckbox>
-[[Category: Cyclin-dependent kinase]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkr_consurf.spt"</scriptWhenChecked>
-[[Category: Single protein]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: Arrowsmith, C H.]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Artz, J D.]]
+  </jmolCheckbox>
-[[Category: Bochkarev, A.]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qkr ConSurf].
-[[Category: Dong, A.]]
+<div style="clear:both"></div>
-[[Category: Edwards, A M.]]
+__TOC__
-[[Category: Hassanali, A.]]
+</StructureSection>
-[[Category: Hui, R.]]
+[[Category: Cryptosporidium parvum Iowa II]]
-[[Category: Lew, J.]]
+[[Category: Large Structures]]
-[[Category: Lin, Y H.]]
+[[Category: Arrowsmith CH]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Artz JD]]
-[[Category: Sundstrom, M.]]
+[[Category: Bochkarev A]]
-[[Category: Weigelt, J.]]
+[[Category: Dong A]]
-[[Category: Wernimont, A K.]]
+[[Category: Edwards AM]]
-[[Category: IXM]]
+[[Category: Hassanali A]]
-[[Category: cp-specific cyclin-dependent kinase]]
+[[Category: Hui R]]
-[[Category: cryptosporidium parvum]]
+[[Category: Lew J]]
-[[Category: malaria]]
+[[Category: Lin YH]]
-[[Category: sgc]]
+[[Category: Sundstrom M]]
-[[Category: structural genomic]]
+[[Category: Weigelt J]]
-[[Category: structural genomics consortium]]
+[[Category: Wernimont AK]]
-[[Category: transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:45:15 2008''