2qkr: Difference between revisions

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New page: left|200px<br /><applet load="2qkr" size="350" color="white" frame="true" align="right" spinBox="true" caption="2qkr, resolution 2.600Å" /> '''Cryptosporidium par...
 
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[[Image:2qkr.jpg|left|200px]]<br /><applet load="2qkr" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2qkr, resolution 2.600&Aring;" />
'''Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound'''<br />


==About this Structure==
==Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound==
2QKR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii] with <scene name='pdbligand=IXM:'>IXM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKR OCA].
<StructureSection load='2qkr' size='340' side='right'caption='[[2qkr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
[[Category: Cryptosporidium parvum iowa ii]]
== Structural highlights ==
[[Category: Cyclin-dependent kinase]]
<table><tr><td colspan='2'>[[2qkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QKR FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
[[Category: Arrowsmith, C.H.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IXM:(Z)-1H,1H-[2,3]BIINDOLYLIDENE-3,2-DIONE-3-OXIME'>IXM</scene></td></tr>
[[Category: Artz, J.D.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qkr OCA], [https://pdbe.org/2qkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qkr RCSB], [https://www.ebi.ac.uk/pdbsum/2qkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qkr ProSAT]</span></td></tr>
[[Category: Bochkarev, A.]]
</table>
[[Category: Dong, A.]]
== Function ==
[[Category: Edwards, A.M.]]
[https://www.uniprot.org/uniprot/Q5CRJ8_CRYPI Q5CRJ8_CRYPI]  
[[Category: Hassanali, A.]]
== Evolutionary Conservation ==
[[Category: Hui, R.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Lew, J.]]
Check<jmol>
[[Category: Lin, Y.H.]]
  <jmolCheckbox>
[[Category: SGC, Structural.Genomics.Consortium.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkr_consurf.spt"</scriptWhenChecked>
[[Category: Sundstrom, M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Weigelt, J.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Wernimont, A.K.]]
  </jmolCheckbox>
[[Category: IXM]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qkr ConSurf].
[[Category: cp-specific cyclin-dependent kinase]]
<div style="clear:both"></div>
[[Category: cryptosporidium parvum]]
__TOC__
[[Category: malaria]]
</StructureSection>
[[Category: sgc]]
[[Category: Cryptosporidium parvum Iowa II]]
[[Category: structural genomics]]
[[Category: Large Structures]]
[[Category: structural genomics consortium]]
[[Category: Arrowsmith CH]]
[[Category: transferase]]
[[Category: Artz JD]]
 
[[Category: Bochkarev A]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:34:53 2008''
[[Category: Dong A]]
[[Category: Edwards AM]]
[[Category: Hassanali A]]
[[Category: Hui R]]
[[Category: Lew J]]
[[Category: Lin YH]]
[[Category: Sundstrom M]]
[[Category: Weigelt J]]
[[Category: Wernimont AK]]

Latest revision as of 14:35, 30 August 2023

Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime boundCryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound

Structural highlights

2qkr is a 1 chain structure with sequence from Cryptosporidium parvum Iowa II. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q5CRJ8_CRYPI

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2qkr, resolution 2.60Å

Drag the structure with the mouse to rotate

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OCA