2q9v: Difference between revisions

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-[[Image:2q9v.gif|left|200px]]
- {{Structure
+==Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase==
-|PDB= 2q9v |SIZE=350|CAPTION= <scene name='initialview01'>2q9v</scene>, resolution 2.00&Aring;
+<StructureSection load='2q9v' size='340' side='right'caption='[[2q9v]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[2q9v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q9V FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-|GENE= MAGI1, BAIAP1, BAP1, TNRC19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q9v OCA], [https://pdbe.org/2q9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q9v RCSB], [https://www.ebi.ac.uk/pdbsum/2q9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q9v ProSAT]</span></td></tr>
-}}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q9/2q9v_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q9v ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase'''
+==See Also==
+*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-Q9V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9V OCA].
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C A.]]
+[[Category: Arrowsmith CA]]
-[[Category: Cooper, C.]]
+[[Category: Cooper C]]
-[[Category: Delft, F von.]]
+[[Category: Doyle DA]]
-[[Category: Doyle, D A.]]
+[[Category: Edwards A]]
-[[Category: Edwards, A.]]
+[[Category: Elkins JM]]
-[[Category: Elkins, J M.]]
+[[Category: Hozjan V]]
-[[Category: Hozjan, V.]]
+[[Category: Kavanagh KL]]
-[[Category: Kavanagh, K L.]]
+[[Category: Oppermann U]]
-[[Category: Oppermann, U.]]
+[[Category: Papagrigoriou E]]
-[[Category: Papagrigoriou, E.]]
+[[Category: Pilka ES]]
-[[Category: Pilka, E S.]]
+[[Category: Sundstrom M]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Weigelt J]]
-[[Category: Sundstrom, M.]]
+[[Category: Von Delft F]]
-[[Category: Weigelt, J.]]
-[[Category: cys ser mutant]]
-[[Category: membrane associated guanylate kinase]]
-[[Category: pdz]]
-[[Category: sgc]]
-[[Category: structural genomics consortium]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:23:37 2008''