2pwz: Difference between revisions

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-[[Image:2pwz.jpg|left|200px]]
- {{Structure
+==Crystal structure of the apo form of E.Coli malate dehydrogenase==
-|PDB= 2pwz |SIZE=350|CAPTION= <scene name='initialview01'>2pwz</scene>, resolution 2.200&Aring;
+<StructureSection load='2pwz' size='340' side='right'caption='[[2pwz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[2pwz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PWZ FirstGlance]. <br>
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-|GENE=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwz OCA], [https://pdbe.org/2pwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pwz RCSB], [https://www.ebi.ac.uk/pdbsum/2pwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwz ProSAT]</span></td></tr>
-|DOMAIN=
+</table>
-|RELATEDENTRY=[[1ie3|1IE3]]
+== Function ==
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwz OCA], [http://www.ebi.ac.uk/pdbsum/2pwz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pwz RCSB]</span>
+[https://www.uniprot.org/uniprot/MDH_ECOLI MDH_ECOLI] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01516]
-}}
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwz_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pwz ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of the apo form of E.Coli malate dehydrogenase'''
+==See Also==
+*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-PWZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWZ OCA].
+[[Category: Escherichia coli K-12]]
-[[Category: Escherichia coli]]
+[[Category: Large Structures]]
-[[Category: Malate dehydrogenase]]
+[[Category: Clarke TA]]
-[[Category: Single protein]]
+[[Category: Hemmings AM]]
-[[Category: Clarke, T A.]]
+[[Category: Richardson DJ]]
-[[Category: Hemmings, A M.]]
+[[Category: Soderberg CAG]]
-[[Category: Richardson, D J.]]
-[[Category: Soderberg, C A.G.]]
-[[Category: apo form of e coli malate dehydrogenase in space group c2]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:41:50 2008''