2pwz: Difference between revisions
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==Crystal structure of the apo form of E.Coli malate dehydrogenase== | |||
<StructureSection load='2pwz' size='340' side='right'caption='[[2pwz]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2pwz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PWZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwz OCA], [https://pdbe.org/2pwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pwz RCSB], [https://www.ebi.ac.uk/pdbsum/2pwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwz ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MDH_ECOLI MDH_ECOLI] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01516] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
== | Check<jmol> | ||
[[2pwz]] is a 4 chain structure | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwz_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pwz ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Malate | *[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]] | ||
[[Category: Escherichia coli | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Clarke | [[Category: Escherichia coli K-12]] | ||
[[Category: Hemmings | [[Category: Large Structures]] | ||
[[Category: Richardson | [[Category: Clarke TA]] | ||
[[Category: Soderberg | [[Category: Hemmings AM]] | ||
[[Category: Richardson DJ]] | |||
[[Category: Soderberg CAG]] |