2pp3: Difference between revisions

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<StructureSection load='2pp3' size='340' side='right'caption='[[2pp3]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2pp3' size='340' side='right'caption='[[2pp3]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pp3]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PP3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pp3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PP3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LGT:L-GLUCARIC+ACID'>LGT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2pp0|2pp0]], [[2pp1|2pp1]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LGT:L-GLUCARIC+ACID'>LGT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pp3 OCA], [https://pdbe.org/2pp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pp3 RCSB], [https://www.ebi.ac.uk/pdbsum/2pp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pp3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pp3 OCA], [https://pdbe.org/2pp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pp3 RCSB], [https://www.ebi.ac.uk/pdbsum/2pp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pp3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TAGAD_SALTY TAGAD_SALTY]] Catalyzes the efficient dehydration of both L-talarate and galactarate to 5-keto-4-deoxy-D-glucarate. Also catalyzes the epimerization of L-talarate to galactarate; epimerization occurs in competition with dehydration. Is required for the utilization of L-talarate as a carbon source. Also functions in galactarate utilization. Is not active on other acid sugars.<ref>PMID:17649980</ref>
[https://www.uniprot.org/uniprot/TAGAD_SALTY TAGAD_SALTY] Catalyzes the efficient dehydration of both L-talarate and galactarate to 5-keto-4-deoxy-D-glucarate. Also catalyzes the epimerization of L-talarate to galactarate; epimerization occurs in competition with dehydration. Is required for the utilization of L-talarate as a carbon source. Also functions in galactarate utilization. Is not active on other acid sugars.<ref>PMID:17649980</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Fedorov, A A]]
[[Category: Almo SC]]
[[Category: Fedorov, E V]]
[[Category: Fedorov AA]]
[[Category: Gerlt, J A]]
[[Category: Fedorov EV]]
[[Category: Yew, W S]]
[[Category: Gerlt JA]]
[[Category: Enolase superfamily]]
[[Category: Yew WS]]
[[Category: L-talarate/galactarate dehydratase]]
[[Category: Lyase]]

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