2pm5: Difference between revisions

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OCA

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 ==Human alpha-defensin 1 derivative (HNP1)==
-<StructureSection load='2pm5' size='340' side='right' caption='[[2pm5]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='2pm5' size='340' side='right'caption='[[2pm5]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2pm5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PM5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PM5 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2pm5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PM5 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DEFA1, DEF1, DEFA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pm5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pm5 OCA], [https://pdbe.org/2pm5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pm5 RCSB], [https://www.ebi.ac.uk/pdbsum/2pm5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pm5 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pm5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pm5 OCA], [http://pdbe.org/2pm5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pm5 RCSB], [http://www.ebi.ac.uk/pdbsum/2pm5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pm5 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/DEF3_HUMAN DEF3_HUMAN] Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.<ref>PMID:15616305</ref> <ref>PMID:2006422</ref> <ref>PMID:15894545</ref> <ref>PMID:17452329</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 21: / Line 22: @@
 ==See Also==
-*[[Defensin|Defensin]]
+*[[Defensin 3D structures|Defensin 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Lu, W]]
+[[Category: Large Structures]]
-[[Category: Lubkowski, J]]
+[[Category: Lu W]]
-[[Category: Pazgier, M]]
+[[Category: Lubkowski J]]
-[[Category: Antimicrobial]]
+[[Category: Pazgier M]]
-[[Category: Antimicrobial protein]]
-[[Category: Defensin]]
-[[Category: Derivative]]