2pkv: Difference between revisions

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-[[Image:2pkv.png|left|200px]]
-<!--
+==D-(GGTATACC) ambient pressure==
-The line below this paragraph, containing "STRUCTURE_2pkv", creates the "Structure Box" on the page.
+<StructureSection load='2pkv' size='340' side='right'caption='[[2pkv]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2pkv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PKV FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pkv OCA], [https://pdbe.org/2pkv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pkv RCSB], [https://www.ebi.ac.uk/pdbsum/2pkv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pkv ProSAT]</span></td></tr>
-{{STRUCTURE_2pkv|  PDB=2pkv  |  SCENE=  }}
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The behaviour of the d(GGTATACC) oligonucleotide has been investigated by X-ray crystallography at 295 K in the range from ambient pressure to 2 GPa (approximately 20,000 atm). Four 3D-structures of the A-DNA form (at ambient pressure, 0.55, 1.09 and 1.39 GPa) were refined at 1.60 or 1.65 A resolution. In addition to the diffraction pattern of the A-form, the broad meridional streaks previously explained by occluded B-DNA octamers within the channels of the crystalline A-form matrix were observed up to at least 2 GPa. This work highlights an important property of nucleic acids, their capability to withstand very high pressures, while keeping in such conditions a nearly invariant geometry of base pairs that store and carry genetic information. The double-helix base-paired architecture behaves as a molecular spring, which makes it especially adapted to very harsh conditions. These features may have contributed to the emergence of a RNA World at prebiotic stage.
-===D-(GGTATACC) ambient pressure===
+Adaptation of the base-paired double-helix molecular architecture to extreme pressure.,Girard E, Prange T, Dhaussy AC, Migianu-Griffoni E, Lecouvey M, Chervin JC, Mezouar M, Kahn R, Fourme R Nucleic Acids Res. 2007;35(14):4800-8. Epub 2007 Jul 7. PMID:17617642<ref>PMID:17617642</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_17617642}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 2pkv" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 17617642 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_17617642}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-[[2pkv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKV OCA].
+[[Category: Fourme R]]
+[[Category: Girard E]]
-==Reference==
+[[Category: Kahn R]]
-<ref group="xtra">PMID:17617642</ref><ref group="xtra">PMID:2911354</ref><ref group="xtra">PMID:11524565</ref><ref group="xtra">PMID:16478683</ref><ref group="xtra">PMID:3586017</ref><references group="xtra"/>
+[[Category: Prange T]]
-[[Category: Fourme, R.]]
-[[Category: Girard, E.]]
-[[Category: Kahn, R.]]
-[[Category: Prange, T.]]
-[[Category: Crystal structure]]
-[[Category: Dna]]
-[[Category: High pressure]]