2pbc: Difference between revisions

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[[Image:2pbc.png|left|200px]]


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==FK506-binding protein 2==
The line below this paragraph, containing "STRUCTURE_2pbc", creates the "Structure Box" on the page.
<StructureSection load='2pbc' size='340' side='right'caption='[[2pbc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2pbc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PBC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
{{STRUCTURE_2pbc| PDB=2pbc |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbc OCA], [https://pdbe.org/2pbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pbc RCSB], [https://www.ebi.ac.uk/pdbsum/2pbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pbc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FKBP2_HUMAN FKBP2_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pbc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pbc ConSurf].
<div style="clear:both"></div>


===FK506-binding protein 2===
==See Also==
 
*[[FKBP 3D structures|FKBP 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2PBC is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBC OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev A]]
[[Category: Butler-Cole, C.]]
[[Category: Butler-Cole C]]
[[Category: Davis, T.]]
[[Category: Davis T]]
[[Category: Dhe-Paganon, S.]]
[[Category: Dhe-Paganon S]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Neculai, D.]]
[[Category: Neculai D]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Sicheri F]]
[[Category: Sicheri, F.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Walker JR]]
[[Category: Walker, J R.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Endoplasmic reticulum]]
[[Category: Isomerase]]
[[Category: Polymorphism]]
[[Category: Rotamase]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:46:10 2009''

Latest revision as of 13:58, 30 August 2023

FK506-binding protein 2FK506-binding protein 2

Structural highlights

2pbc is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FKBP2_HUMAN PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2pbc, resolution 1.80Å

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