2p5y: Difference between revisions

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==Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD==
==Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD==
<StructureSection load='2p5y' size='340' side='right' caption='[[2p5y]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
<StructureSection load='2p5y' size='340' side='right'caption='[[2p5y]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2p5y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P5Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[2p5y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P5Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA0591 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-glucose_4-epimerase UDP-glucose 4-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p5y OCA], [https://pdbe.org/2p5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p5y RCSB], [https://www.ebi.ac.uk/pdbsum/2p5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p5y ProSAT], [https://www.topsan.org/Proteins/RSGI/2p5y TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p5y OCA], [http://pdbe.org/2p5y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p5y RCSB], [http://www.ebi.ac.uk/pdbsum/2p5y PDBsum], [http://www.topsan.org/Proteins/RSGI/2p5y TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5SKQ2_THET8 Q5SKQ2_THET8]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p5/2p5y_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p5/2p5y_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p5y ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Thet8]]
[[Category: Large Structures]]
[[Category: UDP-glucose 4-epimerase]]
[[Category: Thermus thermophilus HB8]]
[[Category: Chen, L]]
[[Category: Chen L]]
[[Category: Chrzas, J]]
[[Category: Chrzas J]]
[[Category: Ebihara, A]]
[[Category: Ebihara A]]
[[Category: Fu, Z-Q]]
[[Category: Fu Z-Q]]
[[Category: Kuramitsu, S]]
[[Category: Kuramitsu S]]
[[Category: Structural genomic]]
[[Category: Rose JP]]
[[Category: Rose, J P]]
[[Category: Shinkai A]]
[[Category: Shinkai, A]]
[[Category: Swindell JT]]
[[Category: Swindell, J T]]
[[Category: Wang B-C]]
[[Category: Wang, B-C]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Zhu J]]
[[Category: Zhu, J]]
[[Category: Isomerase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: PSI, Protein structure initiative]]
[[Category: Rsgi]]
[[Category: Secsg]]
[[Category: Thermus thermophilus hb8]]
[[Category: Ttha0591]]
[[Category: Udp-glucose 4-epimerase]]

Latest revision as of 13:55, 30 August 2023

Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NADCrystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD

Structural highlights

2p5y is a 1 chain structure with sequence from Thermus thermophilus HB8. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.92Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

Q5SKQ2_THET8

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2p5y, resolution 1.92Å

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