2p0a: Difference between revisions

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New page: left|200px<br /> <applet load="2p0a" size="450" color="white" frame="true" align="right" spinBox="true" caption="2p0a, resolution 1.90Å" /> '''The crystal structu...
 
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[[Image:2p0a.gif|left|200px]]<br />
<applet load="2p0a" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2p0a, resolution 1.90&Aring;" />
'''The crystal structure of human synapsin III (SYN3) in complex with AMPPNP'''<br />


==About this Structure==
==The crystal structure of human synapsin III (SYN3) in complex with AMPPNP==
2P0A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with CL, SO4, ANP and EDO as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2P0A OCA].  
<StructureSection load='2p0a' size='340' side='right'caption='[[2p0a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2p0a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P0A FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p0a OCA], [https://pdbe.org/2p0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p0a RCSB], [https://www.ebi.ac.uk/pdbsum/2p0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p0a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYN3_HUMAN SYN3_HUMAN] May be involved in the regulation of neurotransmitter release and synaptogenesis.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p0/2p0a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p0a ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Synapsin|Synapsin]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C.H.]]
[[Category: Arrowsmith CH]]
[[Category: Burgess, N.]]
[[Category: Burgess N]]
[[Category: Delft, F.von.]]
[[Category: Doyle D]]
[[Category: Doyle, D.]]
[[Category: Edwards A]]
[[Category: Edwards, A.]]
[[Category: Elkins JM]]
[[Category: Elkins, J.M.]]
[[Category: Gileadi C]]
[[Category: Gileadi, C.]]
[[Category: Gileadi O]]
[[Category: Gileadi, O.]]
[[Category: Gorrec F]]
[[Category: Gorrec, F.]]
[[Category: Niesen FH]]
[[Category: Niesen, F.H.]]
[[Category: Phillips C]]
[[Category: Phillips, C.]]
[[Category: Pike ACW]]
[[Category: Pike, A.C.W.]]
[[Category: Salah E]]
[[Category: SGC, Structural.Genomics.Consortium.]]
[[Category: Sundstrom M]]
[[Category: Salah, E.]]
[[Category: Turnbull AP]]
[[Category: Sundstrom, M.]]
[[Category: Umeano C]]
[[Category: Turnbull, A.P.]]
[[Category: Weigelt J]]
[[Category: Umeano, C.]]
[[Category: Von Delft F]]
[[Category: Weigelt, J.]]
[[Category: ANP]]
[[Category: CL]]
[[Category: EDO]]
[[Category: SO4]]
[[Category: neurotransmitter release]]
[[Category: schizophrenia]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomics consortium]]
[[Category: synapsin]]
[[Category: vesicle transport ]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 23:18:54 2007''

Latest revision as of 13:51, 30 August 2023

The crystal structure of human synapsin III (SYN3) in complex with AMPPNPThe crystal structure of human synapsin III (SYN3) in complex with AMPPNP

Structural highlights

2p0a is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SYN3_HUMAN May be involved in the regulation of neurotransmitter release and synaptogenesis.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2p0a, resolution 1.90Å

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