2p0a: Difference between revisions

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-[[Image:2p0a.gif|left|200px]]
- {{Structure
+==The crystal structure of human synapsin III (SYN3) in complex with AMPPNP==
-|PDB= 2p0a |SIZE=350|CAPTION= <scene name='initialview01'>2p0a</scene>, resolution 1.90&Aring;
+<StructureSection load='2p0a' size='340' side='right'caption='[[2p0a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
+<table><tr><td colspan='2'>[[2p0a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P0A FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-|GENE= SYN3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-|DOMAIN=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p0a OCA], [https://pdbe.org/2p0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p0a RCSB], [https://www.ebi.ac.uk/pdbsum/2p0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p0a ProSAT]</span></td></tr>
-|RELATEDENTRY=
+</table>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p0a OCA], [http://www.ebi.ac.uk/pdbsum/2p0a PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p0a RCSB]</span>
+== Function ==
-}}
+[https://www.uniprot.org/uniprot/SYN3_HUMAN SYN3_HUMAN] May be involved in the regulation of neurotransmitter release and synaptogenesis.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p0/2p0a_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p0a ConSurf].
+<div style="clear:both"></div>
-'''The crystal structure of human synapsin III (SYN3) in complex with AMPPNP'''
+==See Also==
+*[[Synapsin|Synapsin]]
+__TOC__
-==About this Structure==
+</StructureSection>
-P0A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P0A OCA].
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Arrowsmith CH]]
-[[Category: Burgess, N.]]
+[[Category: Burgess N]]
-[[Category: Delft, F von.]]
+[[Category: Doyle D]]
-[[Category: Doyle, D.]]
+[[Category: Edwards A]]
-[[Category: Edwards, A.]]
+[[Category: Elkins JM]]
-[[Category: Elkins, J M.]]
+[[Category: Gileadi C]]
-[[Category: Gileadi, C.]]
+[[Category: Gileadi O]]
-[[Category: Gileadi, O.]]
+[[Category: Gorrec F]]
-[[Category: Gorrec, F.]]
+[[Category: Niesen FH]]
-[[Category: Niesen, F H.]]
+[[Category: Phillips C]]
-[[Category: Phillips, C.]]
+[[Category: Pike ACW]]
-[[Category: Pike, A C.W.]]
+[[Category: Salah E]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Sundstrom M]]
-[[Category: Salah, E.]]
+[[Category: Turnbull AP]]
-[[Category: Sundstrom, M.]]
+[[Category: Umeano C]]
-[[Category: Turnbull, A P.]]
+[[Category: Weigelt J]]
-[[Category: Umeano, C.]]
+[[Category: Von Delft F]]
-[[Category: Weigelt, J.]]
-[[Category: neurotransmitter release]]
-[[Category: schizophrenia]]
-[[Category: sgc]]
-[[Category: structural genomic]]
-[[Category: structural genomics consortium]]
-[[Category: synapsin]]
-[[Category: vesicle transport]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:26:05 2008''