2op6: Difference between revisions

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-[[Image:2op6.jpg|left|200px]]<br /><applet load="2op6" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="2op6, resolution 1.85&Aring;" />
-'''Peptide-binding domain of Heat shock 70 kDa protein D precursor from C.elegans'''<br />
-==About this Structure==
+==Peptide-binding domain of Heat shock 70 kDa protein D precursor from C.elegans==
-OP6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OP6 OCA].
+<StructureSection load='2op6' size='340' side='right'caption='[[2op6]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2op6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OP6 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2op6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2op6 OCA], [https://pdbe.org/2op6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2op6 RCSB], [https://www.ebi.ac.uk/pdbsum/2op6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2op6 ProSAT], [https://www.topsan.org/Proteins/MCSG/2op6 TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BIBH_CAEEL BIBH_CAEEL] Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Required for ER dynamics during the first embryonic cell divisions (PubMed:15716356). Specifically, controls ER transition into sheet-like structures at the onset of mitosis, possibly by regulating homotypic membrane fusion (PubMed:15716356).[UniProtKB:P11021]<ref>PMID:15716356</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/2op6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2op6 ConSurf].
+<div style="clear:both"></div>
+==See Also==
+*[[Heat Shock Protein structures|Heat Shock Protein structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Caenorhabditis elegans]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Duggan, E.]]
+[[Category: Duggan E]]
-[[Category: Gu, M.]]
+[[Category: Gu M]]
-[[Category: Joachimiak, A.]]
+[[Category: Joachimiak A]]
-[[Category: MCSG, Midwest Center for Structural Genomics.]]
+[[Category: Morimoto RI]]
-[[Category: Morimoto, R I.]]
+[[Category: Osipiuk J]]
-[[Category: Osipiuk, J.]]
+[[Category: Voisine C]]
-[[Category: Voisine, C.]]
-[[Category: apc90014 13]]
-[[Category: hsp70/peptide-binding domain]]
-[[Category: mcsg]]
-[[Category: midwest center for structural genomics]]
-[[Category: protein structure initiative]]
-[[Category: psi-2]]
-[[Category: structural genomics]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:20:59 2008''