2ola: Difference between revisions

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==Crystal structure of O-succinylbenzoic acid synthetase from Staphylococcus aureus, cubic crystal form==
==Crystal structure of O-succinylbenzoic acid synthetase from Staphylococcus aureus, cubic crystal form==
<StructureSection load='2ola' size='340' side='right' caption='[[2ola]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
<StructureSection load='2ola' size='340' side='right'caption='[[2ola]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ola]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OLA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ola]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OLA FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2okt|2okt]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">menc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ola FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ola OCA], [https://pdbe.org/2ola PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ola RCSB], [https://www.ebi.ac.uk/pdbsum/2ola PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ola ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2ola TOPSAN]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/o-succinylbenzoate--CoA_ligase o-succinylbenzoate--CoA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.2.1.26 6.2.1.26] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ola FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ola OCA], [http://pdbe.org/2ola PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ola RCSB], [http://www.ebi.ac.uk/pdbsum/2ola PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2ola TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0H3KH80_STAAE A0A0H3KH80_STAAE] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).[HAMAP-Rule:MF_01933]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ol/2ola_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ol/2ola_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ola ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Staac]]
[[Category: Large Structures]]
[[Category: O-succinylbenzoate--CoA ligase]]
[[Category: Staphylococcus aureus subsp. aureus COL]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Dickey, M]]
[[Category: Dickey M]]
[[Category: Gerlt, J A]]
[[Category: Gerlt JA]]
[[Category: Gheyi, T]]
[[Category: Gheyi T]]
[[Category: Maletic, M]]
[[Category: Maletic M]]
[[Category: Structural genomic]]
[[Category: Ozyurt S]]
[[Category: Ozyurt, S]]
[[Category: Patskovsky Y]]
[[Category: Patskovsky, Y]]
[[Category: Reyes C]]
[[Category: Reyes, C]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: Smith D]]
[[Category: Smith, D]]
[[Category: Wasserman SR]]
[[Category: Wasserman, S R]]
[[Category: Enolase]]
[[Category: Ligase]]
[[Category: Nysgrc]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: O-succinylbenzoic acid synthetase]]
[[Category: PSI, Protein structure initiative]]

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