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[[Image:2ogf.gif|left|200px]]<br /><applet load="2ogf" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2ogf, resolution 1.890&Aring;" />
'''Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372'''<br />


==About this Structure==
==Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372==
2OGF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=OXG:'>OXG</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGF OCA].  
<StructureSection load='2ogf' size='340' side='right'caption='[[2ogf]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ogf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=OXG:8-OXOGUANINE'>OXG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogf OCA], [https://pdbe.org/2ogf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogf RCSB], [https://www.ebi.ac.uk/pdbsum/2ogf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogf ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2ogf TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MPTD_METJA MPTD_METJA] Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).[HAMAP-Rule:MF_02130]<ref>PMID:22931285</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ogf ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Single protein]]
[[Category: Almo SC]]
[[Category: Almo, S C.]]
[[Category: Burley SK]]
[[Category: Burley, S K.]]
[[Category: Ramagopal UA]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Sauder JM]]
[[Category: Ramagopal, U A.]]
[[Category: Toro R]]
[[Category: Sauder, J M.]]
[[Category: Toro, R.]]
[[Category: GOL]]
[[Category: OXG]]
[[Category: SO4]]
[[Category: new york structural genomix research consortium]]
[[Category: nysgxrc]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: structural genomics]]
[[Category: unknown function]]
 
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