2oeo: Difference between revisions

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New page: left|200px {{Structure |PDB= 2oeo |SIZE=350|CAPTION= <scene name='initialview01'>2oeo</scene>, resolution 2.00Å |SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+F...
 
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[[Image:2oeo.jpg|left|200px]]


{{Structure
==Cryogenic crystal structure of Staphylococcal Nuclease variant truncated Delta+PHS I92D==
|PDB= 2oeo |SIZE=350|CAPTION= <scene name='initialview01'>2oeo</scene>, resolution 2.00&Aring;
<StructureSection load='2oeo' size='340' side='right'caption='[[2oeo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+For+Residue+A+301'>AC1</scene> and <scene name='pdbsite=AC2:Thp+Binding+Site+For+Residue+A+300'>AC2</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3&#39;,5&#39;-DIPHOSPHATE'>THP</scene>
<table><tr><td colspan='2'>[[2oeo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OEO FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE= nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00175 SNc]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oeo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oeo OCA], [https://pdbe.org/2oeo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oeo RCSB], [https://www.ebi.ac.uk/pdbsum/2oeo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oeo ProSAT]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oeo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oeo OCA], [http://www.ebi.ac.uk/pdbsum/2oeo PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2oeo RCSB]</span>
</table>
}}
== Function ==
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oe/2oeo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oeo ConSurf].
<div style="clear:both"></div>


'''Cryogenic crystal structure of Staphylococcal Nuclease variant truncated Delta+PHS I92D'''
==See Also==
 
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2OEO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OEO OCA].
[[Category: Large Structures]]
[[Category: Micrococcal nuclease]]
[[Category: Single protein]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Gittis, A G.]]
[[Category: Gittis AG]]
[[Category: Lattman, E E.]]
[[Category: Lattman EE]]
[[Category: Reynald, R L.]]
[[Category: Reynald RL]]
[[Category: hydrolase]]
[[Category: ob-fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 09:51:54 2008''

Latest revision as of 13:36, 30 August 2023

Cryogenic crystal structure of Staphylococcal Nuclease variant truncated Delta+PHS I92DCryogenic crystal structure of Staphylococcal Nuclease variant truncated Delta+PHS I92D

Structural highlights

2oeo is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUC_STAAU Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2oeo, resolution 2.00Å

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