2obo: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==Structure of HEPATITIS C VIRAL NS3 protease domain complexed with NS4A peptide and ketoamide SCH476776==
-<StructureSection load='2obo' size='340' side='right' caption='[[2obo]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
+<StructureSection load='2obo' size='340' side='right'caption='[[2obo]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2obo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OBO FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2obo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C] and [https://en.wikipedia.org/wiki/Hepatitis_C_virus_subtype_1b Hepatitis C virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OBO FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=HUD:TERT-BUTYL+{(2S)-1-[(1R,2S,5S)-2-{[(2S,3R)-4-AMINO-1-CYCLOPROPYL-3-HYDROXY-4-OXOBUTAN-2-YL]CARBAMOYL}-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEX-3-YL]-3,3-DIMETHYL-1-OXOBUTAN-2-YL}CARBAMATE'>HUD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a1r|1a1r]], [[2a4g|2a4g]], [[2a4q|2a4q]], [[2a4r|2a4r]], [[2fm2|2fm2]], [[2f9v|2f9v]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=HUD:TERT-BUTYL+{(2S)-1-[(1R,2S,5S)-2-{[(2S,3R)-4-AMINO-1-CYCLOPROPYL-3-HYDROXY-4-OXOBUTAN-2-YL]CARBAMOYL}-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEX-3-YL]-3,3-DIMETHYL-1-OXOBUTAN-2-YL}CARBAMATE'>HUD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11103 9HEPC])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2obo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obo OCA], [https://pdbe.org/2obo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2obo RCSB], [https://www.ebi.ac.uk/pdbsum/2obo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2obo ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2obo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obo OCA], [http://pdbe.org/2obo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2obo RCSB], [http://www.ebi.ac.uk/pdbsum/2obo PDBsum]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q9QP06_9HEPC Q9QP06_9HEPC]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 17: / Line 19: @@
 </div>
 <div class="pdbe-citations 2obo" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Virus protease 3D structures|Virus protease 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Arasappan, A]]
+[[Category: Hepacivirus C]]
-[[Category: Bennett, F]]
+[[Category: Hepatitis C virus subtype 1b]]
-[[Category: Beyer, B M]]
+[[Category: Large Structures]]
-[[Category: Bogen, S F]]
+[[Category: Arasappan A]]
-[[Category: Chen, K]]
+[[Category: Bennett F]]
-[[Category: Fischmann, T]]
+[[Category: Beyer BM]]
-[[Category: Girijavallabhan, V]]
+[[Category: Bogen SF]]
-[[Category: Guo, Z]]
+[[Category: Chen K]]
-[[Category: Hong, Z]]
+[[Category: Fischmann T]]
-[[Category: Ingram, R]]
+[[Category: Girijavallabhan V]]
-[[Category: Jao, E]]
+[[Category: Guo Z]]
-[[Category: Liu, Y]]
+[[Category: Hong Z]]
-[[Category: Love, R G]]
+[[Category: Ingram R]]
-[[Category: Madison, V]]
+[[Category: Jao E]]
-[[Category: Malcolm, B]]
+[[Category: Liu Y]]
-[[Category: Myers, J]]
+[[Category: Love RG]]
-[[Category: Njoroge, F G]]
+[[Category: Madison V]]
-[[Category: Pichardo, J]]
+[[Category: Malcolm B]]
-[[Category: Prongay, A J]]
+[[Category: Myers Jr J]]
-[[Category: Prosise, W W]]
+[[Category: Njoroge FG]]
-[[Category: Ramanathan, L]]
+[[Category: Pichardo J]]
-[[Category: Saksena, A K]]
+[[Category: Prongay AJ]]
-[[Category: Senior, M]]
+[[Category: Prosise WW]]
-[[Category: Strickland, C]]
+[[Category: Ramanathan L]]
-[[Category: Taremi, S S]]
+[[Category: Saksena AK]]
-[[Category: Venkatraman, S]]
+[[Category: Senior M]]
-[[Category: Weber, P C]]
+[[Category: Strickland C]]
-[[Category: Yang, R]]
+[[Category: Taremi SS]]
-[[Category: Yao, N]]
+[[Category: Venkatraman S]]
-[[Category: Yarosh-Tomaine, T]]
+[[Category: Weber PC]]
-[[Category: Zhang, R]]
+[[Category: Yang R]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Yao N]]
-[[Category: Ketoamide inhibitor]]
+[[Category: Yarosh-Tomaine T]]
-[[Category: Viral protein]]
+[[Category: Zhang R]]