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==Structure and Function Studies of Cytochrome P450 158A1 from Streptomyces coelicolor A3(2)==
==Structure and Function Studies of Cytochrome P450 158A1 from Streptomyces coelicolor A3(2)==
<StructureSection load='2nza' size='340' side='right' caption='[[2nza]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='2nza' size='340' side='right'caption='[[2nza]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2nza]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strco Strco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NZA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2nza]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NZA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2nz5|2nz5]], [[2dkk|2dkk]], [[1t93|1t93]], [[1se6|1se6]], [[1s1f|1s1f]], [[2d09|2d09]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SC8F11.24c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=100226 STRCO])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nza OCA], [https://pdbe.org/2nza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nza RCSB], [https://www.ebi.ac.uk/pdbsum/2nza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nza ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nza OCA], [http://pdbe.org/2nza PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nza RCSB], [http://www.ebi.ac.uk/pdbsum/2nza PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2nza ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/C1581_STRCO C1581_STRCO]] Catalyze oxidative C-C coupling reaction to polymerize flaviolin and form highly conjugated pigments which protect the soil bacterium from deleterious effects of UV irradiation (two isomers of biflaviolin and one triflaviolin).<ref>PMID:17614370</ref>
[https://www.uniprot.org/uniprot/C1581_STRCO C1581_STRCO] Catalyze oxidative C-C coupling reaction to polymerize flaviolin and form highly conjugated pigments which protect the soil bacterium from deleterious effects of UV irradiation (two isomers of biflaviolin and one triflaviolin).<ref>PMID:17614370</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Cytochrome P450|Cytochrome P450]]
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Strco]]
[[Category: Large Structures]]
[[Category: Waterman, M R]]
[[Category: Waterman MR]]
[[Category: Zhao, B]]
[[Category: Zhao B]]
[[Category: C-c coupling activity]]
[[Category: Cyp158a1]]
[[Category: Cytochrome p450 oxidoreductase]]
[[Category: Flaviolin]]
[[Category: Oxidoreductase]]
[[Category: Streptomyce]]

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