2ijj: Difference between revisions

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==Crystal structure analysis of ColE1 ROM mutant F14Y==
==Crystal structure analysis of ColE1 ROM mutant F14Y==
<StructureSection load='2ijj' size='340' side='right' caption='[[2ijj]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2ijj' size='340' side='right'caption='[[2ijj]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ijj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IJJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ijj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IJJ FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ijh|2ijh]], [[2iji|2iji]], [[2ijk|2ijk]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rop ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ijj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ijj OCA], [https://pdbe.org/2ijj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ijj RCSB], [https://www.ebi.ac.uk/pdbsum/2ijj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ijj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ijj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ijj OCA], [http://pdbe.org/2ijj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ijj RCSB], [http://www.ebi.ac.uk/pdbsum/2ijj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ijj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX]] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.  
[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Ladner, J E]]
[[Category: Large Structures]]
[[Category: Cole1]]
[[Category: Ladner JE]]
[[Category: Rna-recognition]]
[[Category: Rom]]
[[Category: Rop]]
[[Category: Transcription regulator]]

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