2hc9: Difference between revisions

==Structure of Caenorhabditis elegans leucine aminopeptidase-zinc complex (LAP1)==

<StructureSection load='2hc9' size='340' side='right'caption='[[2hc9]], [[Resolution|resolution]] 1.85&Aring;' scene=''>

== Structural highlights ==

<table><tr><td colspan='2'>[[2hc9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HC9 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hc9 OCA], [https://pdbe.org/2hc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hc9 RCSB], [https://www.ebi.ac.uk/pdbsum/2hc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hc9 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2hc9 TOPSAN]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/AMPL_CAEEL AMPL_CAEEL] Probably acts as a digestive enzyme.

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hc/2hc9_consurf.spt"</scriptWhenChecked>

    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

  </jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hc9 ConSurf].

<div style="clear:both"></div>

==See Also==

*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]

</StructureSection>

[[Category: Large Structures]]

[[Category: Almo SC]]

[[Category: Burley SK]]

[[Category: Milstein S]]

[[Category: Patskovsky Y]]

[[Category: Ramagopal U]]

[[Category: Vidal M]]

[[Category: Wengerter BC]]

[[Category: Zhan C]]