2hc9: Difference between revisions

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[[Image:2hc9.gif|left|200px]]


{{Structure
==Structure of Caenorhabditis elegans leucine aminopeptidase-zinc complex (LAP1)==
|PDB= 2hc9 |SIZE=350|CAPTION= <scene name='initialview01'>2hc9</scene>, resolution 1.85&Aring;
<StructureSection load='2hc9' size='340' side='right'caption='[[2hc9]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2hc9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HC9 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Leucyl_aminopeptidase Leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.1 3.4.11.1] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
|GENE= lap-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00433 Peptidase_M17]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hc9 OCA], [https://pdbe.org/2hc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hc9 RCSB], [https://www.ebi.ac.uk/pdbsum/2hc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hc9 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2hc9 TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hc9 OCA], [http://www.ebi.ac.uk/pdbsum/2hc9 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2hc9 RCSB]</span>
</table>
}}
== Function ==
[https://www.uniprot.org/uniprot/AMPL_CAEEL AMPL_CAEEL] Probably acts as a digestive enzyme.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hc/2hc9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hc9 ConSurf].
<div style="clear:both"></div>


'''Structure of Caenorhabditis elegans leucine aminopeptidase-zinc complex (LAP1)'''
==See Also==
 
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2HC9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HC9 OCA].
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Leucyl aminopeptidase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Almo SC]]
[[Category: Almo, S C.]]
[[Category: Burley SK]]
[[Category: Burley, S K.]]
[[Category: Milstein S]]
[[Category: Milstein, S.]]
[[Category: Patskovsky Y]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Ramagopal U]]
[[Category: Patskovsky, Y.]]
[[Category: Vidal M]]
[[Category: Ramagopal, U.]]
[[Category: Wengerter BC]]
[[Category: Vidal, M.]]
[[Category: Zhan C]]
[[Category: Wengerter, B C.]]
[[Category: Zhan, C.]]
[[Category: aminopeptidase]]
[[Category: carbonate]]
[[Category: new york structural genomix research consortium]]
[[Category: nysgxrc]]
[[Category: peptidase]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
[[Category: zinc]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:28:36 2008''

Latest revision as of 12:55, 30 August 2023

Structure of Caenorhabditis elegans leucine aminopeptidase-zinc complex (LAP1)Structure of Caenorhabditis elegans leucine aminopeptidase-zinc complex (LAP1)

Structural highlights

2hc9 is a 1 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

AMPL_CAEEL Probably acts as a digestive enzyme.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2hc9, resolution 1.85Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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