2h2b: Difference between revisions

<StructureSection load='2h2b' size='340' side='right'caption='[[2h2b]], [[Resolution|resolution]] 1.60&Aring;' scene=''>

<table><tr><td colspan='2'>[[2h2b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H2B FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h2b OCA], [https://pdbe.org/2h2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h2b RCSB], [https://www.ebi.ac.uk/pdbsum/2h2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h2b ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ZO1_HUMAN ZO1_HUMAN] The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.<ref>PMID:21240187</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Appleton BA]]

[[Category: Hunziker W]]

[[Category: Sidhu SS]]

[[Category: Skelton NJ]]

[[Category: Wiesmann C]]

[[Category: Wu P]]

[[Category: Yin JP]]

[[Category: Zhang Y]]