2h0l: Difference between revisions

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-[[Image:2h0l.png|left|200px]]
-{{STRUCTURE_2h0l|  PDB=2h0l  |  SCENE=  }}
+==Crystal Structure of a Mutant of Rat Annexin A5==
+<StructureSection load='2h0l' size='340' side='right'caption='[[2h0l]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
-===Crystal Structure of a Mutant of Rat Annexin A5===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2h0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H0L FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-[[2h0l]] is a 1 chain structure of [[Annexin]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H0L OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h0l OCA], [https://pdbe.org/2h0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h0l RCSB], [https://www.ebi.ac.uk/pdbsum/2h0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h0l ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ANXA5_RAT ANXA5_RAT] This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h0/2h0l_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h0l ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Annexin|Annexin]]
+*[[Annexin 3D structures|Annexin 3D structures]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Rattus norvegicus]]
-[[Category: Brisson, A.]]
+[[Category: Brisson A]]
-[[Category: Estaintot, B Langlois D.]]
+[[Category: Gallois B]]
-[[Category: Gallois, B.]]
+[[Category: Granier T]]
-[[Category: Granier, T.]]
+[[Category: Langlois D'Estaintot B]]
-[[Category: Tessier, B.]]
+[[Category: Tessier B]]
-[[Category: Blood clotting]]
-[[Category: Phospholipid membrane binding protein]]