2gzi: Difference between revisions
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==Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)== | |||
<StructureSection load='2gzi' size='340' side='right'caption='[[2gzi]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2gzi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GZI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gzi OCA], [https://pdbe.org/2gzi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gzi RCSB], [https://www.ebi.ac.uk/pdbsum/2gzi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gzi ProSAT]</span></td></tr> | ||
[[2gzi]] | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/IMM9_ECOLX IMM9_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gz/2gzi_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gzi ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Colicin|Colicin]] | *[[Colicin 3D structures|Colicin 3D structures]] | ||
*[[Colicin | *[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Hemmings AM]] | ||
[[Category: Hemmings | [[Category: Kleanthous C]] | ||
[[Category: Kleanthous | [[Category: Kolade OO]] | ||
[[Category: Kolade | [[Category: Kuhlmann UC]] | ||
[[Category: Kuhlmann | [[Category: Santi PS]] | ||
[[Category: Santi | |||
Latest revision as of 12:49, 30 August 2023
Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)
Structural highlights
FunctionIMM9_ECOLX This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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