2gug: Difference between revisions

New page: left|200px<br /><applet load="2gug" size="450" color="white" frame="true" align="right" spinBox="true" caption="2gug, resolution 2.28Å" /> '''NAD-dependent format...
 
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[[Image:2gug.gif|left|200px]]<br /><applet load="2gug" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2gug, resolution 2.28&Aring;" />
'''NAD-dependent formate dehydrogenase from Pseudomonas sp.101 in complex with formate'''<br />


==About this Structure==
==NAD-dependent formate dehydrogenase from Pseudomonas sp.101 in complex with formate==
2GUG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.] with PG4, FMT and PEG as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Formate_dehydrogenase Formate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.2 1.2.1.2] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2GUG OCA].
<StructureSection load='2gug' size='340' side='right'caption='[[2gug]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
[[Category: Formate dehydrogenase]]
== Structural highlights ==
[[Category: Pseudomonas sp.]]
<table><tr><td colspan='2'>[[2gug]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._101 Pseudomonas sp. 101]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GUG FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
[[Category: Boiko, K.M.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
[[Category: Filippova, E.V.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gug OCA], [https://pdbe.org/2gug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gug RCSB], [https://www.ebi.ac.uk/pdbsum/2gug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gug ProSAT]</span></td></tr>
[[Category: Polyakov, K.M.]]
</table>
[[Category: Popov, V.O.]]
== Function ==
[[Category: Tikhonova, T.V.]]
[https://www.uniprot.org/uniprot/FDH_PSESR FDH_PSESR]  
[[Category: Tishkov, V.I.]]
== Evolutionary Conservation ==
[[Category: FMT]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: PEG]]
Check<jmol>
[[Category: PG4]]
  <jmolCheckbox>
[[Category: nad+(a))]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/2gug_consurf.spt"</scriptWhenChecked>
[[Category: oxidoreductase (aldehude (d)]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gug ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 11:23:55 2007''
==See Also==
*[[Formate dehydrogenase 3D structures|Formate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas sp. 101]]
[[Category: Boiko KM]]
[[Category: Filippova EV]]
[[Category: Polyakov KM]]
[[Category: Popov VO]]
[[Category: Tikhonova TV]]
[[Category: Tishkov VI]]

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