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==Crystal structure of a HDAC-like protein with 9,9,9-trifluoro-8-oxo-N-phenylnonan amide bound==
==Crystal structure of a HDAC-like protein with 9,9,9-trifluoro-8-oxo-N-phenylnonan amide bound==
<StructureSection load='2gh6' size='340' side='right' caption='[[2gh6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2gh6' size='340' side='right'caption='[[2gh6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gh6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcsd Alcsd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GH6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GH6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gh6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenaceae_bacterium_FB188 Alcaligenaceae bacterium FB188]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GH6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GH6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CF3:9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE'>CF3</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.203&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zz0|1zz0]], [[1zz1|1zz1]], [[1zz3|1zz3]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CF3:9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE'>CF3</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hdaH, hdaH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=242601 ALCSD])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gh6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gh6 OCA], [https://pdbe.org/2gh6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gh6 RCSB], [https://www.ebi.ac.uk/pdbsum/2gh6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gh6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gh6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gh6 OCA], [http://pdbe.org/2gh6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gh6 RCSB], [http://www.ebi.ac.uk/pdbsum/2gh6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gh6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HDAH_ALCSD HDAH_ALCSD]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2gh6" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2gh6" style="background-color:#fffaf0;"></div>
==See Also==
*[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alcsd]]
[[Category: Alcaligenaceae bacterium FB188]]
[[Category: Ficner, R]]
[[Category: Large Structures]]
[[Category: Hildmann, C]]
[[Category: Ficner R]]
[[Category: Nielsen, T K]]
[[Category: Hildmann C]]
[[Category: Riester, D]]
[[Category: Nielsen TK]]
[[Category: Schwienhorst, A]]
[[Category: Riester D]]
[[Category: Wegener, D]]
[[Category: Schwienhorst A]]
[[Category: Histone deacetylase]]
[[Category: Wegener D]]
[[Category: Hydrolase]]
[[Category: Trifluoromethyl ketone]]
[[Category: Zinc-ion]]

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