2gf0: Difference between revisions

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-[[Image:2gf0.png|left|200px]]
-{{STRUCTURE_2gf0|  PDB=2gf0  |  SCENE=  }}
+==The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state==
+<StructureSection load='2gf0' size='340' side='right'caption='[[2gf0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-===The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2gf0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF0 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[2gf0]] is a 4 chain structure of [[GTP-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [https://pdbe.org/2gf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DIRA1_HUMAN DIRA1_HUMAN] Displays low GTPase activity and exist predominantly in the GTP-bound form.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf0_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gf0 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[GTP-binding protein|GTP-binding protein]]
+*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Arrowsmith, C.]]
+[[Category: Large Structures]]
-[[Category: Bray, J.]]
+[[Category: Arrowsmith C]]
-[[Category: Delft, F von.]]
+[[Category: Bray J]]
-[[Category: Doyle, D.]]
+[[Category: Doyle D]]
-[[Category: Edwards, A.]]
+[[Category: Edwards A]]
-[[Category: Elkins, J.]]
+[[Category: Elkins J]]
-[[Category: Fedorov, O.]]
+[[Category: Fedorov O]]
-[[Category: Gileadi, O.]]
+[[Category: Gileadi O]]
-[[Category: Niesen, F E.]]
+[[Category: Niesen FE]]
-[[Category: Papagrigoriou, E.]]
+[[Category: Papagrigoriou E]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Salah E]]
-[[Category: Salah, E.]]
+[[Category: Schoch G]]
-[[Category: Schoch, G.]]
+[[Category: Sundstrom M]]
-[[Category: Sundstrom, M.]]
+[[Category: Turnbull AP]]
-[[Category: Turnbull, A P.]]
+[[Category: Weigelt J]]
-[[Category: Weigelt, J.]]
+[[Category: Wen-Hwa L]]
-[[Category: Wen-Hwa, L.]]
+[[Category: Yang X]]
-[[Category: Yang, X.]]
+[[Category: Von Delft F]]
-[[Category: Dira]]
-[[Category: Gdp/gtp binding]]
-[[Category: Gtp hydrolysis]]
-[[Category: Sgc]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]
-[[Category: Transport protein]]