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==Crystal structure of human RAB1A in complex with GDP== | |||
<StructureSection load='2fol' size='340' side='right'caption='[[2fol]], [[Resolution|resolution]] 2.63Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2fol]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FOL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.631Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fol OCA], [https://pdbe.org/2fol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fol RCSB], [https://www.ebi.ac.uk/pdbsum/2fol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fol ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RAB1A_HUMAN RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/2fol_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fol ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | |||
< | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith | [[Category: Large Structures]] | ||
[[Category: Bochkarev | [[Category: Arrowsmith C]] | ||
[[Category: Edwards | [[Category: Bochkarev A]] | ||
[[Category: Park | [[Category: Edwards A]] | ||
[[Category: Park H]] | |||
[[Category: Shen | [[Category: Shen L]] | ||
[[Category: Shen | [[Category: Shen Y]] | ||
[[Category: Sundstrom | [[Category: Sundstrom M]] | ||
[[Category: Tempel | [[Category: Tempel W]] | ||
[[Category: Wang | [[Category: Wang J]] | ||
[[Category: Weigelt | [[Category: Weigelt J]] | ||
Latest revision as of 12:30, 30 August 2023
Crystal structure of human RAB1A in complex with GDPCrystal structure of human RAB1A in complex with GDP
Structural highlights
FunctionRAB1A_HUMAN Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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