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| <StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='96/960003/Cv/1'>
| | See [[Tenofovir disoproxil]] or [[Biktarvy]] |
| Tenofovir disoproxil, sold under the trade name Viread among others, is a medication used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. See also [https://en.wikipedia.org/wiki/Tenofovir_disoproxil].
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| Tenofovir disoproxil is a prodrug that is quickly absorbed from the gut and cleaved to release tenofovir. Inside cells, tenofovir is phosphorylated to tenofovir diphosphate (which is analogous to a triphosphate, as tenofovir itself already has one phosphonate residue), the active compound that inhibits reverse transcriptase via chain termination. | |
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| <scene name='96/960003/Bindingsite/3'>Tenofovir diphosphate binding site</scene> at reverse transcriptase ([[3fkb]]).
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| </StructureSection>
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| == References ==
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| <references/>
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Latest revision as of 16:01, 29 August 2023