Phosphoribosyltransferase 3D structures: Difference between revisions
Michal Harel (talk | contribs) New page: ==3D structures of phosphoribosyltransferase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *'''Orotate phosphor... |
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**[[2pry]] - yOPRT – yeast<br /> | **[[2pry]] - yOPRT – yeast<br /> | ||
**[[1oro]] - EcOPRT – ''Escherichia coli''<br /> | **[[1oro]], [[6tai]] - EcOPRT – ''Escherichia coli''<br /> | ||
**[[1j7j]] - StOPRT – ''Salmonella typhimurium''<br /> | **[[1j7j]] - StOPRT – ''Salmonella typhimurium''<br /> | ||
**[[2aee]] - OPRT – ''Streptococcus pyogenes''<br /> | **[[2aee]] - OPRT – ''Streptococcus pyogenes''<br /> | ||
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**[[5hkf]] - MtOPRT + PRPP<BR /> | **[[5hkf]] - MtOPRT + PRPP<BR /> | ||
**[[5hkl]] - MtOPRT (mutant) + Pi<BR /> | **[[5hkl]] - MtOPRT (mutant) + Pi<BR /> | ||
**[[6taj]], [[6tak]] - EcOPRT + orotate <BR /> | |||
*'''Hypoxanthine-guanine phosphoribosyltransferase''' | *'''Hypoxanthine PRT''' | ||
*[[7cmj]] - LdHPRT – ''Leishmania donovani''<br /> | |||
*'''Hypoxanthine-guanine phosphoribosyltransferase or purine/pyrimidine PRT''' | |||
**[[1z7g]] - hHPRT <br /> | **[[1z7g]] - hHPRT <br /> | ||
**[[1nul]], [[1grv]] - EcHPRT <br /> | **[[1nul]], [[1grv]], [[8cag]] - EcHPRT <br /> | ||
**[[1dbr]] - TgHPRT – ''Toxoplasma gondii''<br /> | **[[1dbr]] - TgHPRT – ''Toxoplasma gondii''<br /> | ||
**[[1tc1]] - TcHPRT – ''Trypanosoma cruzi''<br /> | **[[1tc1]] - TcHPRT – ''Trypanosoma cruzi''<br /> | ||
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*Hypoxanthine-guanine phosphoribosyltransferase binary complex with nucleotide | *Hypoxanthine-guanine phosphoribosyltransferase binary complex with nucleotide | ||
**[[1hmp]] - hHGPRT + GMP - human<br /> | **[[1hmp]] - hHGPRT + GMP - human<br /> | ||
**[[3gep]], [[3ggj]], [[4jit]], [[4jls]] - hHGPRT + guanine derivative<br /> | **[[3gep]], [[3ggj]], [[4jit]], [[4jls]] - hHGPRT + guanine derivative<br /> | ||
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**[[1y0b]] - BsHGPRT + GTP – ''Bacillus subtilis''<br /> | **[[1y0b]] - BsHGPRT + GTP – ''Bacillus subtilis''<br /> | ||
**[[2fxv]] - BsHGPRT + GMP<br /> | **[[2fxv]] - BsHGPRT + GMP<br /> | ||
**[[6w1i]] - BsHGPRT + PPGPP<br /> | |||
**[[3kb8]] - BaHGPRT + GMP<br /> | **[[3kb8]] - BaHGPRT + GMP<br /> | ||
**[[6d9s]] - BaHGPRT + PPGPP<br /> | **[[6d9s]] - BaHGPRT + PPGPP<br /> | ||
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**[[3ggc]] - hHGPRT + hypoxanthine derivative<br /> | **[[3ggc]] - hHGPRT + hypoxanthine derivative<br /> | ||
**[[4ijq]], [[4rab]], [[4rac]], [[4rad]], [[4ran]], [[4rao]], [[4raq]], [[6bnj]], | **[[4ijq]], [[4rab]], [[4rac]], [[4rad]], [[4ran]], [[4rao]], [[4raq]], [[6bnj]], [[5w8v]], [[5hia]], [[7san]] - hHGPRT + inhibitor<br /> | ||
**[[5bsk]], [[5brn]] - hHGPRT (mutant) + nucleoside phosphonate <br /> | **[[5bsk]], [[5brn]] - hHGPRT (mutant) + nucleoside phosphonate <br /> | ||
**[[4kn6]] - hHGPRT + antiviral agent<br /> | **[[4kn6]] - hHGPRT + antiviral agent<br /> | ||
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**[[4z1o]] - SsHGPRT + PRPP - Sulfolobus solfataricus<br /> | **[[4z1o]] - SsHGPRT + PRPP - Sulfolobus solfataricus<br /> | ||
**[[6bo7]] - HGPRT + inhibitor – Plasmodium vivax<br /> | **[[6bo7]] - HGPRT + inhibitor – Plasmodium vivax<br /> | ||
**[[6aqo]], [[6ar9]], [[6apv]], [[6apu]], [[6apt]], [[6aps]], [[5kap]], [[5k51]], [[5jsq]] - TbHGPRT + inhibitor <br /> | **[[6aqo]], [[6ar9]], [[6apv]], [[6apu]], [[6apt]], [[6aps]], [[5kap]], [[5k51]], [[5jsq]], [[7sb7]] - TbHGPRT + inhibitor <br /> | ||
*Hypoxanthine-guanine phosphoribosyltransferase ternary complex | *Hypoxanthine-guanine phosphoribosyltransferase ternary complex | ||
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**[[5bqo]] - SsHGXPRT <br /> | **[[5bqo]] - SsHGXPRT <br /> | ||
**[[5bqp]] - SsHGXPRT + pyrophosphate <br /> | **[[5bqp]] - SsHGXPRT + pyrophosphate <br /> | ||
**[[7kl6]], [[7kl7]] - HpHGXPRT <br /> | |||
**[[7tux]] - PfHGXPRT + inhibitor<br /> | |||
**[[7scr]] - TbHGXPRT + inhibitor<br /> | |||
**[[8fwy]] - TcHGXPRT + xanthine + Pi<br /> | |||
**[[8fwz]], [[8fx0]], [[8fx1]], [[8fx2]], [[8fx3]] - TcHGXPRT + inhibitor<br /> | |||
*'''Quinolinic acid phosphoribosyltransferase''' | *'''Quinolinic acid phosphoribosyltransferase''' | ||
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**[[1v9s]] - TtUPRT <br /> | **[[1v9s]] - TtUPRT <br /> | ||
**[[2e55]] - UPRT – ''Aquifex aeolicus'' <br /> | **[[2e55]] - UPRT – ''Aquifex aeolicus'' <br /> | ||
**[[6wn8]] - UPRT – ''Klebsiella pneumoniae'' <br /> | |||
**[[2ehj]] - EcUPRT <br /> | **[[2ehj]] - EcUPRT <br /> | ||
**[[3dmp]] - UPRT – ''Burkholderia pseudomallei'' | **[[3dmp]] - UPRT – ''Burkholderia pseudomallei'' | ||
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**[[1i5e]], [[2igb]] - UPRT + UMP – ''Bacillus caldolyticus''<br /> | **[[1i5e]], [[2igb]] - UPRT + UMP – ''Bacillus caldolyticus''<br /> | ||
**[[1o5o]] - TmUPRT + UMP<br /> | **[[1o5o]] - TmUPRT + UMP<br /> | ||
**[[1vst]], [[3g6w]] - SsUPRT + GTP + PRPP | **[[1vst]], [[3g6w]] - SsUPRT + GTP + PRPP <br /> | ||
**[[7rh8]] - UPRT + UTP – ''Candida albicans''<br /> | |||
*'''Adenine phosphoribosyltransferase''' | *'''Adenine phosphoribosyltransferase''' | ||
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**[[6hgp]] – hAPRT <br /> | **[[6hgp]] – hAPRT <br /> | ||
**[[1g2p]], [[1g2q]] – yAPRT <br /> | **[[1g2p]], [[1g2q]] – yAPRT <br /> | ||
**[[1qcc]], [[1qcd]] - LdAPRT | **[[1qcc]], [[1qcd]] - LdAPRT <br /> | ||
**[[2dy0]] - EcAPRT <br /> | **[[2dy0]] - EcAPRT <br /> | ||
**[[4lza]] – APRT – ''Thermoanaerobacter pseudethanolicus''<br /> | **[[4lza]] – APRT – ''Thermoanaerobacter pseudethanolicus''<br /> | ||
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**[[4trb]] – SsAPRT <br /> | **[[4trb]] – SsAPRT <br /> | ||
**[[5yw2]] - FtAPRT <br /> | **[[5yw2]] - FtAPRT <br /> | ||
**[[5zgo]] - TtAPRT <br /> | **[[5zgo]], [[6fsp]] - TtAPRT <br /> | ||
*Adenine phosphoribosyltransferase complex | *Adenine phosphoribosyltransferase complex | ||
**[[7y94]] - hAPRT + adenine<br /> | |||
**[[1ore]], [[1zn8]], [[1zn9]], [[6fcl]] - hAPRT + AMP<br /> | **[[1ore]], [[1zn8]], [[1zn9]], [[6fcl]] - hAPRT + AMP<br /> | ||
**[[4x44]], [[4x45]] - hAPRT (mutant) + AMP <br /> | **[[4x44]], [[4x45]] - hAPRT (mutant) + AMP <br /> | ||
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**[[1l1q]] - GiAPRT + adenine derivative<br /> | **[[1l1q]] - GiAPRT + adenine derivative<br /> | ||
**[[1l1r]] - GiAPRT + adenine derivative + PRPP<BR /> | **[[1l1r]] - GiAPRT + adenine derivative + PRPP<BR /> | ||
**[[7xi2]] - EcAPRT + Pi<br /> | |||
*'''Nicotinate mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase''' | *'''Nicotinate mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase''' | ||
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*'''Anthranilate phosphoribosyltransferase''' | *'''Anthranilate phosphoribosyltransferase''' | ||
**[[7dsm]] – yANPRT<BR /> | |||
**[[7dsp]] – yANPRT (mutant) <BR /> | |||
**[[1o17]] - SsANPRT <br /> | **[[1o17]] - SsANPRT <br /> | ||
**[[1khd]] – PcANPRT – ''Pectobacterium carotovorum''<br /> | **[[1khd]] – PcANPRT – ''Pectobacterium carotovorum''<br /> | ||
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**[[4gtn]] – AcANPRT – ''Acinetobacter''<br /> | **[[4gtn]] – AcANPRT – ''Acinetobacter''<br /> | ||
**[[5nof]], [[5noe]] – ANPRT – ''Thermococcus kodkarensis''<br /> | **[[5nof]], [[5noe]] – ANPRT – ''Thermococcus kodkarensis''<br /> | ||
**[[8bfr]] – EcANPRT<BR /> | |||
*Anthranilate phosphoribosyltransferase complex containing anthranilate | *Anthranilate phosphoribosyltransferase complex containing anthranilate | ||
**[[7dso]], [[7dsr]] - yANPRT + anthranilate derivative<BR /> | |||
**[[4owm]], [[4own]], [[4owo]], [[4owq]], [[4ows]], [[4owu]], [[4n5v]], [[4n93]] - MtANPRT + PRPP + anthranilate derivative<BR /> | **[[4owm]], [[4own]], [[4owo]], [[4owq]], [[4ows]], [[4owu]], [[4n5v]], [[4n93]] - MtANPRT + PRPP + anthranilate derivative<BR /> | ||
**[[4ij1]], [[4m0r]], [[4owv]], [[4n8q]] - MtANPRT + anthranilate derivative <br /> | **[[4ij1]], [[4m0r]], [[4owv]], [[4n8q]] - MtANPRT + anthranilate derivative <br /> | ||
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*Anthranilate phosphoribosyltransferase other complexes | *Anthranilate phosphoribosyltransferase other complexes | ||
**[[7dsj]] - yANPRT + PRPP<BR /> | |||
**[[1kgz]] - PcANPRT + PRPP<BR /> | **[[1kgz]] - PcANPRT + PRPP<BR /> | ||
**[[1zvw]], [[5byt]], [[5c1r]], [[5c7s]] - MtANPRT + PRPP<BR /> | **[[1zvw]], [[5byt]], [[5c1r]], [[5c7s]] - MtANPRT + PRPP<BR /> | ||
**[[4x58]], [[4x59]], [[4x5b]] - MtANPRT (mutant) + PRPP<BR /> | **[[4x58]], [[4x59]], [[4x5b]] - MtANPRT (mutant) + PRPP<BR /> | ||
**[[4ztv]], [[5bne]], [[5bo2]], [[5bo3]] - MtANPRT + inhibitor <BR /> | |||
**[[3qqs]], [[3qs8]], [[3qsa]], [[3r6c]], [[3r88]], [[3twp]], [[3uu1]], [[4zof]], [[4zoj]], [[4zok]] - MtANPRT + inhibitor + PRPP<BR /> | |||
**[[4x5c]] - MtANPRT (mutant) + PRPP + POP<BR /> | **[[4x5c]] - MtANPRT (mutant) + PRPP + POP<BR /> | ||
**[[1zxy]] - SsANPRT + PRPP<BR /> | **[[1zxy]] - SsANPRT + PRPP<BR /> | ||
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**[[1gxb]] - SsANPRT + POP<br /> | **[[1gxb]] - SsANPRT + POP<br /> | ||
**[[2gvq]] - SsANPRT + anthranilate<br /> | **[[2gvq]] - SsANPRT + anthranilate<br /> | ||
**[[ | **[[8bft]] - EcANPRT + OBGe peptide <BR /> | ||
*'''ATP phosphoribosyltransferase''' See [[ATP Phosphoribosyl Transferase]] | *'''ATP phosphoribosyltransferase''' See [[ATP Phosphoribosyl Transferase]] | ||
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**[[2gvj]] - hNMPRT + FK-866<br /> | **[[2gvj]] - hNMPRT + FK-866<br /> | ||
**[[2e5c]] - hNMPRT + PRPP<BR /> | **[[2e5c]] - hNMPRT + PRPP<BR /> | ||
**[[2e5d]] - hNMPRT + nicotinamide<br /> | **[[2e5d]], [[8dsi]] - hNMPRT + nicotinamide<br /> | ||
**[[3dgr]] - hNMPRT + ADP analog<br /> | **[[3dgr]] - hNMPRT + ADP analog<br /> | ||
**[[4jnm]], [[4jr5]], [[4kfn]], [[4kfo]], [[4kfp]], [[4lts]], [[4lv9]], [[4lva]], [[4lvb]], [[4lvd]], [[4lvf]], [[4lvg]], [[4lww]], [[4m6p]], [[4m6q]], [[4n9b]], [[4n9c]], [[4n9d]], [[4n9e]], [[4l4l]], [[4l4m]], [[4o0z]], [[4o10]], [[4o12]], [[4o13]], [[4o14]], [[4o15]], [[4o16]], [[4o17]], [[4o18]], [[4o19]], [[4o1a]], [[4o1b]], [[4o1c]], [[4o1d]], [[4wq6]], [[4o28]], [[5kit]], [[5u2m]], [[5u2n]], [[5upe]], [[5upf]], [[6e68]], [[5wi1]], [[5wi0]], [[6b76]], [[6b75]], [[6atb]] - hNMPRT + inhibitor<br /> | **[[4jnm]], [[4jr5]], [[4kfn]], [[4kfo]], [[4kfp]], [[4lts]], [[4lv9]], [[4lva]], [[4lvb]], [[4lvd]], [[4lvf]], [[4lvg]], [[4lww]], [[4m6p]], [[4m6q]], [[4n9b]], [[4n9c]], [[4n9d]], [[4n9e]], [[4l4l]], [[4l4m]], [[4o0z]], [[4o10]], [[4o12]], [[4o13]], [[4o14]], [[4o15]], [[4o16]], [[4o17]], [[4o18]], [[4o19]], [[4o1a]], [[4o1b]], [[4o1c]], [[4o1d]], [[4wq6]], [[4o28]], [[5kit]], [[5u2m]], [[5u2n]], [[5upe]], [[5upf]], [[6e68]], [[5wi1]], [[5wi0]], [[6azj]], [[6b76]], [[6b75]], [[6atb]], [[6peb]], [[6tac]], [[7ppe]], [[7ppf]], [[7ppg]], [[7pph]], [[7ppi]], [[8dsm]] - hNMPRT + inhibitor<br /> | ||
**[[7enq]], [[8dtj]] - hNMPRT + activator<br /> | |||
**[[8dsc]], [[8dsd]] - hNMPRT + nicotinamide + activator<br /> | |||
**[[8dsh]] - hNMPRT + AMPcP + activator<br /> | |||
**[[3dhd]], [[3dhf]] - hNMPRT + pyrophosphate + NMN<BR /> | **[[3dhd]], [[3dhf]] - hNMPRT + pyrophosphate + NMN<BR /> | ||
**[[3dkj]], [[3dkl]] - hNMPRT + benzamide + PRPP<BR /> | **[[3dkj]], [[3dkl]] - hNMPRT + benzamide + PRPP<BR /> | ||
**[[6ta0]] - hNMPRT + nicotinic acid + PRPP<BR /> | |||
**[[6ta2]] - hNMPRT + nicotinic acid + phosphate<BR /> | |||
**[[5nsd]], [[5lx5]], [[5lx3]] - hNMPRT + piperidine derivative<br /> | **[[5nsd]], [[5lx5]], [[5lx3]] - hNMPRT + piperidine derivative<br /> | ||
**[[2h3d]] - mNMPRT + NMN<BR /> | **[[2h3d]] - mNMPRT + NMN<BR /> | ||
**[[7q8t]] - mNMPRT + inhibitor<br /> | |||
**[[2g96]] - rNMPRT + NMN<BR /> | **[[2g96]] - rNMPRT + NMN<BR /> | ||
**[[2g97]], [[3g8e]] - rNMPRT + FK-866<br /> | **[[2g97]], [[3g8e]] - rNMPRT + FK-866<br /> | ||