Phospholipase A1: Difference between revisions
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<StructureSection load=' | <StructureSection load='7ezz' size='340' side='right' caption='Phospholiase A1 complex with octylglucoside, glycerol and Ca+2 ion (green) (PDB code [[5dqz]])' scene=''> | ||
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'''Phospholipase A1''' (PLA1) hydrolyzes phospholipids to produce 2-acyl-lysophospholipids and fatty acids<ref>PMID:25436551</ref>. PLA1 preferentially hydrolyzes phosphatidic acid and PLA1-phosphatidic acid regulates mitochondria dynamics<ref>PMID:24599962</ref>. | '''Phospholipase A1''' (PLA1) hydrolyzes phospholipids to produce 2-acyl-lysophospholipids and fatty acids<ref>PMID:25436551</ref>. PLA1 preferentially hydrolyzes phosphatidic acid and PLA1-phosphatidic acid regulates mitochondria dynamics<ref>PMID:24599962</ref>. | ||
== Relevance == | == Relevance == | ||
Phosphatidylserine-specific PLA1 expression in colorectal cancer is associated with tumor invasion and metastasis<ref>PMID:25750298</ref>. | |||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
[[4qnn]] – PLA1 – hornet <br /> | |||
[[2yij]] – PLA1 IIγ – ''Arabidopsis thaliana'' <br /> | [[2yij]] – PLA1 IIγ – ''Arabidopsis thaliana'' <br /> | ||
[[7x0c]], [[7x0d]] – PLA1 – ''Capsicum annuum''<br /> | |||
[[4hyq]] – PLA1 – ''Streptomyces albidoflavus'' <br /> | [[4hyq]] – PLA1 – ''Streptomyces albidoflavus'' <br /> | ||
[[ | [[7ezz]] – PLA1 – ''Salmonella typhi'' <br /> | ||
== References == | == References == |