Phospholipase A1: Difference between revisions

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<StructureSection load='5dqx' size='340' side='right' caption='Caption for this structure' scene=''>
<StructureSection load='7ezz' size='340' side='right' caption='Phospholiase A1 complex with octylglucoside, glycerol and Ca+2 ion (green) (PDB code [[5dqz]])' scene=''>




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'''Phospholipase A1''' (PLA1) hydrolyzes phospholipids to produce 2-acyl-lysophospholipids and fatty acids<ref>PMID:25436551</ref>.  PLA1 preferentially hydrolyzes phosphatidic acid and PLA1-phosphatidic acid regulates mitochondria dynamics<ref>PMID:24599962</ref>.
'''Phospholipase A1''' (PLA1) hydrolyzes phospholipids to produce 2-acyl-lysophospholipids and fatty acids<ref>PMID:25436551</ref>.  PLA1 preferentially hydrolyzes phosphatidic acid and PLA1-phosphatidic acid regulates mitochondria dynamics<ref>PMID:24599962</ref>.
== Disease ==


== Relevance ==
== Relevance ==


== Structural highlights ==
Phosphatidylserine-specific PLA1 expression in colorectal cancer is associated with tumor invasion and metastasis<ref>PMID:25750298</ref>.




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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}


[[4qnn]] – PLA1 – hornet <br />
[[2yij]] – PLA1 IIγ – ''Arabidopsis thaliana'' <br />
[[2yij]] – PLA1 IIγ – ''Arabidopsis thaliana'' <br />
[[7x0c]], [[7x0d]] – PLA1 – ''Capsicum annuum''<br />
[[4hyq]] – PLA1 – ''Streptomyces albidoflavus'' <br />
[[4hyq]] – PLA1 – ''Streptomyces albidoflavus'' <br />
[[4qnn]] – PLA1 – hornet <br />
[[7ezz]] – PLA1 – ''Salmonella typhi'' <br />
[[5dqx]] – PLA1 – ''Salmonella typhi'' <br />


== References ==
== References ==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman