Phosphoglycerate dehydrogenase: Difference between revisions
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'''Phosphoglycerate dehydrogenase''' (PGDH) catalyzes the conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate. This is the first step of serine biosynthesis<ref>PMID:11567059</ref>. NAD is used as cofactor. | '''Phosphoglycerate dehydrogenase''' (PGDH) catalyzes the conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate. This is the first step of serine biosynthesis<ref>PMID:11567059</ref>. NAD is used as cofactor. | ||
See also:[[3-Phosphoglycerates: serine, glycine, cysteine]] | |||
== Relevance == | == Relevance == | ||
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</StructureSection> | </StructureSection> | ||
==3D structures of phosphoglycerate dehydrogenase== | ==3D structures of phosphoglycerate dehydrogenase== | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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*Phosphoglycerate dehydrogenase binary complex | *Phosphoglycerate dehydrogenase binary complex | ||
**[[2g76]] - h3-PGDH + NAD – human<br /> | **[[2g76]], [[7cvp]] - h3-PGDH + NAD – human<br /> | ||
**[[5n53]], [[5nzo]], [[5nzp]], [[5nzq]], [[5ofv]], [[5ofw]] – h3-PGDH + drug<br /> | **[[5n53]], [[5nzo]], [[5nzp]], [[5nzq]], [[5ofv]], [[5ofw]], [[7ewh]] – h3-PGDH + drug<br /> | ||
**[[5ofm]] – h3-PGDH + amino-methyl-indole<br /> | **[[5ofm]] – h3-PGDH + amino-methyl-indole<br /> | ||
**[[7va1]] – h3-PGDH + thiazole derivative<br /> | |||
**[[7dkm]] – h3-PGDH + inhibitor<br /> | |||
**[[1sc6]], [[2p9c]], [[2p9e]], [[2p9g]] - EcPGDH (mutant) + NAD – ''Escherichia coli''<br /> | **[[1sc6]], [[2p9c]], [[2p9e]], [[2p9g]] - EcPGDH (mutant) + NAD – ''Escherichia coli''<br /> | ||
**[[1yba]] - EcPGDH + NAD<br /> | **[[1yba]] - EcPGDH + NAD<br /> | ||