2y8s: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-==CO-STRUCTURE OF AN AMA1 MUTANT (Y230A) WITH A SURFACE EXPOSED REGION OF RON2 FROM TOXOPLASMA GONDII==
-<StructureSection load='2y8s' size='340' side='right' caption='[[2y8s]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
+==Co-structure of an AMA1 mutant (Y230A) with a surface exposed region of RON2 from Toxoplasma gondii==
+<StructureSection load='2y8s' size='340' side='right'caption='[[2y8s]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2y8s]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y8S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y8S FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2y8s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y8S FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BO3:BORIC+ACID'>BO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y8t|2y8t]], [[2y8r|2y8r]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BO3:BORIC+ACID'>BO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y8s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y8s RCSB], [http://www.ebi.ac.uk/pdbsum/2y8s PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y8s OCA], [https://pdbe.org/2y8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y8s RCSB], [https://www.ebi.ac.uk/pdbsum/2y8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y8s ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/AMA1_TOXGV AMA1_TOXGV] Essential microneme protein that plays an important role in host cell invasion. Part of the moving junction (MJ) complex, a ringlike structure formed between the plasma membranes of the apical tip of the parasite and the target host cell. During invasion, the MJ migrates from the anterior to the posterior of the parasite, leading to internalization of the parasite into a parasitophorous vacuole (PV).<ref>PMID:11083833</ref> <ref>PMID:11087913</ref> <ref>PMID:16000372</ref> <ref>PMID:16102004</ref> <ref>PMID:16244709</ref> <ref>PMID:19247437</ref> <ref>PMID:20421941</ref> <ref>PMID:21205639</ref> <ref>PMID:22523242</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 15: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2y8s" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
 __TOC__
 </StructureSection>
+[[Category: Large Structures]]
 [[Category: Toxoplasma gondii]]
-[[Category: Boulanger, M J]]
+[[Category: Boulanger MJ]]
-[[Category: Crawford, J]]
+[[Category: Crawford J]]
-[[Category: Douguet, D]]
+[[Category: Douguet D]]
-[[Category: Lamarque, M H]]
+[[Category: Lamarque MH]]
-[[Category: Lebrun, M]]
+[[Category: Lebrun M]]
-[[Category: Pugniere, M]]
+[[Category: Pugniere M]]
-[[Category: Roques, M]]
+[[Category: Roques M]]
-[[Category: Tonkin, M L]]
+[[Category: Tonkin ML]]
-[[Category: Invasion]]
-[[Category: Membrane protein]]
-[[Category: Moving junction]]