2y05: Difference between revisions
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==Crystal structure of human leukotriene B4 12-hydroxydehydrogenase in complex with NADP and raloxifene== | ==Crystal structure of human leukotriene B4 12-hydroxydehydrogenase in complex with NADP and raloxifene== | ||
<StructureSection load='2y05' size='340' side='right' caption='[[2y05]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2y05' size='340' side='right'caption='[[2y05]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2y05]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2y05]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y05 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=RAL:RALOXIFENE'>RAL</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=RAL:RALOXIFENE'>RAL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y05 OCA], [https://pdbe.org/2y05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y05 RCSB], [https://www.ebi.ac.uk/pdbsum/2y05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y05 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PTGR1_HUMAN PTGR1_HUMAN] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith C]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: Edwards | [[Category: Edwards A]] | ||
[[Category: Johansson | [[Category: Johansson C]] | ||
[[Category: Krojer | [[Category: Krojer T]] | ||
[[Category: Oppermann | [[Category: Oppermann U]] | ||
[[Category: Pike | [[Category: Pike ACW]] | ||
[[Category: Savitsky | [[Category: Savitsky P]] | ||
[[Category: Sethi | [[Category: Sethi R]] | ||
[[Category: Shafqat | [[Category: Shafqat N]] | ||
[[Category: Weigelt | [[Category: Weigelt J]] | ||
[[Category: Yue | [[Category: Yue WW]] | ||
[[Category: | [[Category: Von Delft F]] | ||