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==Structure of E.coli rhomboid protease GlpG, active site mutant, S201T, orthorhombic crystal form==
==Structure of E.coli rhomboid protease GlpG, active site mutant, S201T, orthorhombic crystal form==
<StructureSection load='2xtv' size='340' side='right' caption='[[2xtv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2xtv' size='340' side='right'caption='[[2xtv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xtv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XTV FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xtv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XTV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ic8|2ic8]], [[2xov|2xov]], [[2xtu|2xtu]], [[2xow|2xow]], [[2irv|2irv]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtv OCA], [https://pdbe.org/2xtv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xtv RCSB], [https://www.ebi.ac.uk/pdbsum/2xtv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xtv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtv OCA], [http://pdbe.org/2xtv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xtv RCSB], [http://www.ebi.ac.uk/pdbsum/2xtv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xtv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecobd]]
[[Category: Large Structures]]
[[Category: Rhomboid protease]]
[[Category: Vinothkumar KR]]
[[Category: Vinothkumar, K R]]
[[Category: Hydrolase]]
[[Category: Membrane protein]]

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