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==GCN4 leucine zipper, mutation of Lys15 to epsilon-azido-Lys== | |||
<StructureSection load='2ahp' size='340' side='right'caption='[[2ahp]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
| | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ahp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AHP FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=AZK:(S)-2-AMINO-6-AZIDOHEXANOIC+ACID'>AZK</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ahp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ahp OCA], [https://pdbe.org/2ahp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ahp RCSB], [https://www.ebi.ac.uk/pdbsum/2ahp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ahp ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'. | |||
==See Also== | |||
*[[Gcn4 3D Structures|Gcn4 3D Structures]] | |||
*[[Gnc4 3D Structures|Gnc4 3D Structures]] | |||
== | __TOC__ | ||
</StructureSection> | |||
[[ | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: | [[Category: Ghadiri MR]] | ||
[[Category: | [[Category: Horne WS]] | ||
[[Category: | |||
[[Category: | |||
Latest revision as of 10:59, 23 August 2023
GCN4 leucine zipper, mutation of Lys15 to epsilon-azido-LysGCN4 leucine zipper, mutation of Lys15 to epsilon-azido-Lys
Structural highlights
FunctionGCN4_YEAST Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'. See Also |
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