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[[Image:2f7f.gif|left|200px]]<br /><applet load="2f7f" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2f7f, resolution 2.00&Aring;" />
'''Crystal structure of Enterococcus faecalis putative nicotinate phosphoribosyltransferase, NEW YORK STRUCTURAL GENOMICS CONSORTIUM'''<br />


==About this Structure==
==Crystal structure of Enterococcus faecalis putative nicotinate phosphoribosyltransferase, NEW YORK STRUCTURAL GENOMICS CONSORTIUM==
2F7F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis_v583 Enterococcus faecalis v583] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=NIO:'>NIO</scene>, <scene name='pdbligand=DPO:'>DPO</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Nicotinate_phosphoribosyltransferase Nicotinate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.11 2.4.2.11] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F7F OCA].
<StructureSection load='2f7f' size='340' side='right'caption='[[2f7f]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Enterococcus faecalis v583]]
== Structural highlights ==
[[Category: Nicotinate phosphoribosyltransferase]]
<table><tr><td colspan='2'>[[2f7f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F7F FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Almo, S C.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NIO:NICOTINIC+ACID'>NIO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Burley, S K.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f7f OCA], [https://pdbe.org/2f7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f7f RCSB], [https://www.ebi.ac.uk/pdbsum/2f7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f7f ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2f7f TOPSAN]</span></td></tr>
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
</table>
[[Category: Patskovsky, Y.]]
== Function ==
[[Category: DPO]]
[https://www.uniprot.org/uniprot/Q830Y8_ENTFA Q830Y8_ENTFA] Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP (By similarity).[SAAS:SAAS007229_004_012126]
[[Category: GOL]]
== Evolutionary Conservation ==
[[Category: NIO]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: SO4]]
Check<jmol>
[[Category: new york structural genomix research consortium]]
  <jmolCheckbox>
[[Category: nysgxrc]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/2f7f_consurf.spt"</scriptWhenChecked>
[[Category: protein structure initiative]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: psi]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: structural genomics]]
  </jmolCheckbox>
[[Category: transferase]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f7f ConSurf].
 
<div style="clear:both"></div>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:18:29 2008''
__TOC__
</StructureSection>
[[Category: Enterococcus faecalis V583]]
[[Category: Large Structures]]
[[Category: Almo SC]]
[[Category: Burley SK]]
[[Category: Patskovsky Y]]

Latest revision as of 10:44, 23 August 2023

Crystal structure of Enterococcus faecalis putative nicotinate phosphoribosyltransferase, NEW YORK STRUCTURAL GENOMICS CONSORTIUMCrystal structure of Enterococcus faecalis putative nicotinate phosphoribosyltransferase, NEW YORK STRUCTURAL GENOMICS CONSORTIUM

Structural highlights

2f7f is a 1 chain structure with sequence from Enterococcus faecalis V583. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

Q830Y8_ENTFA Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP (By similarity).[SAAS:SAAS007229_004_012126]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2f7f, resolution 2.00Å

Drag the structure with the mouse to rotate

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