2b82: Difference between revisions

<StructureSection load='2b82' size='340' side='right'caption='[[2b82]], [[Resolution|resolution]] 1.25&Aring;' scene=''>

<table><tr><td colspan='2'>[[2b82]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1rmw 1rmw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B82 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b82 OCA], [https://pdbe.org/2b82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b82 RCSB], [https://www.ebi.ac.uk/pdbsum/2b82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b82 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/APHA_ECOLI APHA_ECOLI] Dephosphorylates several organic phosphate monoesters including 3'- and 5'-nucleotides, 2'-deoxy-5'-nucleotides, pNPP, phenyl phosphate, glycerol 2-phosphate, ribose 5-phosphate, O-phospho-L-amino acids and phytic acid, showing the highest activity with aryl phosphoesters (pNPP, phenyl phosphate and O-phospho-L-tyrosine), and to a lesser extent with 3'- and 5'-nucleotides. No activity toward ATP, phosphodiesters, glycerol-1-phosphate, glucose 1-phosphate, glucose 6-phosphate, NADP, GTP or 3',5'-cAMP, ADP or ATP. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds. Capable of transferring phosphate from either pNPP or UMP to adenosine or uridine. Does not exhibit nucleotide phosphomutase activity.<ref>PMID:9011040</ref> <ref>PMID:16297670</ref>  

     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b8/2b82_consurf.spt"</scriptWhenChecked>

*[[Acid phosphatase 3D structures|Acid phosphatase 3D structures]]

[[Category: Escherichia coli]]

[[Category: Large Structures]]

[[Category: Benvenuti M]]

[[Category: Calderone V]]

[[Category: Forleo C]]

[[Category: Mangani S]]

[[Category: Rossolini GM]]

[[Category: Thaller MC]]