2b5u: Difference between revisions

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[[Image:2b5u.gif|left|200px]]<br /><applet load="2b5u" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2b5u, resolution 2.300&Aring;" />
'''Crystal Structure Of Colicin E3 V206C Mutant In Complex With Its Immunity Protein'''<br />


==About this Structure==
==Crystal Structure Of Colicin E3 V206C Mutant In Complex With Its Immunity Protein==
2B5U is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=CIT:'>CIT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5U OCA].  
<StructureSection load='2b5u' size='340' side='right'caption='[[2b5u]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2b5u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B5U FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5u OCA], [https://pdbe.org/2b5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b5u RCSB], [https://www.ebi.ac.uk/pdbsum/2b5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5u ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CEA3_ECOLX CEA3_ECOLX] Inactivates ribosomes by hydrolyzing 16S RNA in 30S ribosomes at a specific site.  Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/2b5u_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b5u ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Colicin 3D structures|Colicin 3D structures]]
*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Jakes, K.]]
[[Category: Jakes K]]
[[Category: Nan, W.]]
[[Category: Nallini Vijayarangan A]]
[[Category: Nithianantham, S.]]
[[Category: Nan W]]
[[Category: Shoham, M.]]
[[Category: Nithianantham S]]
[[Category: Vijayarangan, A Nallini.]]
[[Category: Shoham M]]
[[Category: CIT]]
[[Category: colicin e3]]
[[Category: high resolution crystal structure]]
[[Category: immunity protein]]
[[Category: ribosome inactivation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:34:30 2008''

Latest revision as of 10:34, 23 August 2023

Crystal Structure Of Colicin E3 V206C Mutant In Complex With Its Immunity ProteinCrystal Structure Of Colicin E3 V206C Mutant In Complex With Its Immunity Protein

Structural highlights

2b5u is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CEA3_ECOLX Inactivates ribosomes by hydrolyzing 16S RNA in 30S ribosomes at a specific site. Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2b5u, resolution 2.30Å

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